Four crossbred wethers were utilized in a randomized block design to test Thiopeptin, an antibiotic, at .25% of the amount of wheat given, two levels of NaHCO3 (2 and 4%) expressed as a percentage of the wheat given, and a combination of the Thiopeptin (.25%) plus 2% NaHCO3. Acidosis was induced in the four sheep (controls) by feeding cracked soft white wheat at 50 g/kgBW -Ts divided among thre...

Background: Urine and serum alkalization with sodium bicarbonate (NaHCO3) is the initial treatment for salicylate toxicity. Due to medication shortages, sufficient quantities of NaHCO3 may not be available and alternative treatments may be needed. Case Report: This is an observational case report of a man who presented with chronic, inadvertent aspirin intoxication. Initially, we used a NaHCO3 ...

The use of nutritional supplements to improve sporting performance and increase training adaptations is commonplace among athletes and is an expanding market in terms of product choice and availability. The purpose of this study was to examine the effects of 2 ergogenic aids with extracellular blood buffering potential, namely sodium bicarbonate (NaHCO3) and a lactate supplement, during a 40-km...

1. This study was designed to test the hypothesis that acid-base status affects the response to a loop diuretic in human subjects. The renal responses to bumetanide (1 mg intravenously) were studied in eight normal subjects consuming a constant diet supplemented for 3 days on three separate occasions with equivalent quantities of NaCl, NaHCO3 (metabolic alkalosis) or NH4Cl (metabolic acidosis)....

Hydroponic culture solutions containing bicarbonate (HCO3 ) may be used to screen crops such as soybeans (Glycine max) for resistance to iron (Fe) deficiency or chlorosis. Some successful methods use sodium bicarbonate (NaHCO3) in combination with elevated partial pressures of carbon dioxide (CO2) to buffer pH and elevate bicarbonate. Replacing NaHCO3 with magnesium bicarbonate [Mg(HCO3)2] as t...

A large proportion of empirical research and reviews investigating the ergogenic potential of sodium bicarbonate (NaHCO3) supplementation have focused predominately on performance outcomes and only speculate about underlying mechanisms responsible for any benefit. The aim of this review was to critically evaluate the influence of NaHCO3 supplementation on mechanisms associated with skeletal mus...

A study was conducted to evaluate the effectiveness of NaHCO3 and trona in beef cattle diets. Trace element (n = 28) analysis revealed no toxicological or safety concerns with the use of trona. Trona was more (P less than .05) soluble in ruminal fluid than Na2CO3, and NaHCO3 and had greater (P less than .05) buffering capacity (9.6 meq/g) than NaHCO3 (6.1 meq/g) but less (P less than .05) than ...

We proposed an hypothesis that ruminants attempt to select a diet that promotes high levels of feed intake by maintaining optimal ruminal conditions. Three tests of the hypothesis considered whether the diet selection of sheep given either a choice of two high energy density (ED) feeds or a choice between a high and a low ED feed is affected by 1) sodium bicarbonate inclusion (NaHCO3; 1, 2, and...

The role of sediment-bound organic phosphorus (Po) on lake eutrophication was studied using sequential extraction and enzymatic hydrolysis by collecting sediments from Dianchi Lake, China. Bioavailable Po species including labile monoester P, diester P, and phytate-like P were identified in the sequential extractions by H2O, NaHCO3, and NaOH. For the H2O-Po, 36.7% (average) was labile monoester...

Because endothelin receptor inhibition blunts increased distal tubule acidification induced by dietary acid, we examined whether endothelin-1 (ET-1) increases acidification of in vivo perfused distal tubules of anesthetized rats. ET-1 was infused intra-aortically (1.4 pmol ⋅ kg-1 ⋅ min-1) into control animals and into those with increased distal tubule HCO3 secretion induced by drinking 80 mM N...