Usually mathematicians use Hodgkin-Huxley model or FitzHug-Nagumo model to simulate action potentials of skeletal muscle fibers. These models are electrically excitable, but skeletal muscle fibers are stimulated chemically. To investigate skeletal muscle fibers we use a model with six ordinary differential equations. This dynamical system is sensitive to initial value of some variables so it is...

The electrophysiology of cardiac myocytes is tightly coupled to mechanics. One aspect of this is apparent in the effects of mechanical strain on cardiac action potential dynamics. These can be considered through adjustments to classic electrophysiological models. The standard FitzHugh Nagumo model is a reduced two-variable model from Hodgkin-Huxley that can reproduce basic mechanisms of action ...

The paper proposes a new mathematical FitzHugh—Nagumo model with memory, which describes the propagation of nerve impulse in membrane. consists an integro-differential equation initial conditions (the Cauchy problem). difference kernel (memory function) was chosen as power function so that it can be rewritten terms fractional derivative. For problem, explicit finite-difference scheme is constru...

We study a sigmoidal version of the FitzHugh-Nagumo reaction-diffusion system based on an analytic description using piecewise linear approximations of the reaction kinetics. We completely describe the dynamics of wave fronts and discuss the properties of the speed equation. The speed diagrams show front bifurcations between branches with one, three, or five fronts that differ significantly fro...

We address the classical problem of propagation failure for monotonic fronts of the discrete Nagumo equation. For a special class of nonlinearities that support unpinned “translationally invariant” stationary monotonic fronts, we prove that propagation failure cannot occur. Properties of travelling fronts in the discrete Nagumo equation with such special nonlinear functions appear to be similar...

Chaos is an important applied area in nonlinear dynamical systems and it is applicable to many real-world systems including the biological systems. Nerve membranes are known to exhibit their own nonlinear dynamics which generate and propagate action potentials. Such nonlinear dynamics in nerve membranes can produce chaos in neurons and related bifurcations. In 1952, A.L. Hodgkin and A.F. Huxley...

We characterize numerically the regime of anticipated synchronization in the coupled FitzHugh-Nagumo model for neurons. We consider two neurons, coupled unidirectionally (in a master-slave configuration), subject to the same random external forcing and with a recurrent inhibitory delayed connection in the slave neuron. We show that the scheme leads to anticipated synchronization, a regime in wh...