abstract mutations have been described in all of the four open reading frames of the hepatitis b virus (hbv), however, from a clinical perspective the surface escape mutant is the most troublesome. hepatitis b surface antigen (hbsag) variants may impair diagnosis, or allow the virus to escape vaccine-induced immunity or passive immunoglobulin therapy. hbv mutants with amino acid substitutions, ...

Closure of donor site of the flap has special problems. Reduction of this site will decrease the morbidity of operation. In this study, we present our experience in donor site size reduction. METHODS Between 2006 and 2008, 15 patients with skin and soft tissue defects underwent operation. In all patients, coverage of defect was performed with various flaps. Substratum horizontal mat-tress sut...

BACKGROUND Those considering donating or receiving gametes are required to undergo counselling to ensure that they are aware of and consider the psychosocial, emotional and ethical complexities of donor conception before proceeding. AIMS The aim of this study was to evaluate gamete donors' and recipients' views about donor counselling and beliefs about disclosure of the use of donor gametes t...

background: blood transfusion plays a great role in public health and the blood safety still has remained a main concern. hbv has been considered as one of the most prevalent blood borne infections. it is estimated that chronic hbv affects 350-400 million people worldwide. comprehensive knowledge about hbv has high importance in iran due to high number of blood dependent patients. material and ...

advances in nephrology and pediatric urology have increased the number of children who survive renal disease and become candidates for renal transplantation. ten years of experience in pediatric renal transplantation are reviewed to determine the rates of patient morbidity and graft survival. of the 450 renal transplantations performed in imam reza hospital (1989- 1999), fifty-one were done on ...

This article investigates the relationship between grandparents and lesbian daughters in the context of childbirth, looking specifically at the role that pregnancy plays in shaping kinship affinities. Gender, sex, and heterosexuality are fundamental to Euro-American kinship discourse and practice; lesbian couples' parenthood through donor conception represents a significant departure from preva...

objective(s) there are some reports in recent years indicating that renal ischemia - reperfusion (ir) induces deleterious changes in remote organs such as liver. the aim of this study was to investigate whether leukocytes have a role on the induction of oxidative stress in liver after renal ir. materials and methods inbred mice in ir donor group were subjected to renal ir injury. in sham donor ...

background: there are no data on the frequency and biochemical expression of the hemochromatosis associated mutations, c282y and h63d, in iranian adult population. this is the first study among iranians that may advocate a screening program. materials and methods: we investigated the frequency of the c282y/h63d hfe gene mutations in a group of 1029 randomly selected iranian blood donors as well...