γδ T cells are not MHC restricted, elicit cytotoxicity against various malignancies, are present in early post-transplant phases in novel stem cell transplantation strategies and have been shown to mediate antibody-dependent cellular cytotoxicity (ADCC) with monoclonal antibodies (mAbs). These features make γδ T cells promising effector cells for antibody-based immunotherapy in pediatric patien...

Iron regulatory proteins (IRPs) are iron-regulated RNA binding proteins that, along with iron-responsive elements (IREs), control the translation of a diverse set of mRNA with 5' IRE. Dysregulation of IRP action causes disease with etiology that may reflect differential control of IRE-containing mRNA. IREs are defined by a conserved stem-loop structure including a midstem bulge at C8 and a term...

BACKGROUND AND AIMS In crops other than sugarcane there is good evidence that the size and activity of carbon sinks influence source activity via sugar-related regulation of the enzymes of photosynthesis, an effect that is partly mediated through coarse regulation of gene expression. METHODS In the current study, leaf shading treatments were used to perturb the source-sink balance in 12-month...

In a previously reported model study, sugarcane was genetically engineered with the pat gene conferring resistance to the herbicide Buster®. The sugarcane cultivar used in that work was NCo310, which is no longer grown commercially but responds well to tissue culture and transformation. The field performance of the herbicide resistant sugarcane was assessed and stable transgene expression obser...

BACKGROUND The role of advanced glycation end products (AGEs) in the development of diabetes, especially diabetic complications, has been emphasized in many reports. Accumulation of AGEs in the vasculature triggers a series of morphological and functional changes in endothelial cells (ECs) and induces an increase of endothelial permeability. This study was to investigate the involvement of RhoA...

Context. A new large sample of 895 s-process-rich candidates out 454 180 giant stars surveyed by LAMOST at a low spectral resolution ( R ~ 1800) has been reported Norfolk et al. (2019, MNRAS, 490, 2219; hereafter N19). Aims. This study is aimed confirming the s-process enrichment higher 86 000) offered HERMES- Mercator spectrograph for 15 brightest targets N19 sample, which consists 13 Sr-only ...

Introduction: Endoscopy is an invasive and painful procedure in children. Since children can not tolerate pain and stress, sedation is necessary in pediatric endoscopy. The aim of this study was comparison of propofol versus intravenous midazolam for reducing anxiety in children.   Materials and Methods: In this study, 103 patients (2-14 years old) in whom endoscopy was indicated were divid...