Anesthesiology, V 123 • No 2 246 August 2015 T HE heart is not only a pumping organ but also an endocrine organ. B-type natriuretic peptide (BNP) is secreted primarily by cardiac ventricular myocytes in response to increased ventricular wall stress induced by volume expansion, pressure overload, or ischemia.1 BNP protein formation begins with intracellular translation into a large preprohormone...

The aim of the study was to evaluate the clinical usefulness of N-terminal pro-brain natriuretic peptide (NT-Pro BNP) and nitric oxide (NO) with echocardiography (gold standard test) in diagnosis of canine cardiomyopathy. Out of 374 cases, 82 cases showing cardiovascular abnormalities including 16 cases of cardiomyopathy were further selected for standardization of biomarkers. Significant (P

AIMS In women with congenital heart disease (CHD), cardiovascular complications during pregnancy are common, but the risk assessment of these patients remains difficult. This study sought to determine the independent role of N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in addition to other parameters in predicting adverse cardiovascular events during pregnancy in women with CHD....

BACKGROUND AND PURPOSE Premature death after transient ischemic attack or stroke is more often because of heart disease or cancer than stroke. Previous studies found blood biomarkers not usefully predictive of nonfatal stroke but possibly of all-cause death. This association might be explained by potentially treatable occult cardiac disease or cancer. We therefore aimed to validate the associat...

The objective: to study changes and prognostic significance of the blood NT-proBNP in patients with pulmonary sepsis. Subjects Methods. included 34 aged 54.5 ± 2.9 years sepsis or septic shock. Lethality intensive care unit (ICU) was 47.1%. NT-proBNP, procalcitonin (PCT) levels, lactate hemodynamic parameters were registered on 1st day (stage 1) 4th-5th ICU stay 2). Hemodynamics assessed throug...

N-terminal pro-brain natriuretic peptide, C-reactive protein, and uri-nary albumin levels as predictors of mortality and cardiovascular events in older adults. impact of plasma N-terminal pro-brain natriuretic pep-tide in severe chronic congestive heart failure: a substudy of the carvedilol prospective randomized cumulative survival (COPERNICUS) Studies of cardiopulmonary bypass in children: im...