Myocardial bridge (MB) is a congenital variation of the coronary arteries and the segment of the coronary artery through myocardium is compressed during systole. Although it is relatively asymptomatic, percutaneous coronary intervention (PCI) may be necessary to relieve symptoms. Perforation or frank rupture of coronary arteries occurs rarely in patients undergoing percutaneous coronary interve...

a 74-year-old male patient was admitted to our emergency department with post-mi angina. on account of the anginal complaint that continued for three days, a coronary artery angiography was undertaken. a percutaneous transluminal coronary angioplasty was performed, followed by the implantation of a coronary stent, and coronary perfusion (timi-3) was achieved in the left anterior descending arte...

Left ventricular free wall rupture is an uncommon but catastrophic event caused by acute myocardial infarction. In most of the cases, acute rupture results in cardiac tamponade and shock which is usually fatal within few minutes. Only immediate diagnosis and surgery can increase the survival rate. We report the case of the acute left ventricular free wall rupture, which was treated surgically w...

Ventricular septal rupture is still a rare but often fatal complication of acute myocardial infarction. Emergent surgical closure of postinfarction ventricular septal rupture irrespective of the clinical status has been the standard treatment so far. A percutaneous approach using an occluder device is a less invasive option and allows immediate complete closure after initial hemodynamic stabili...

Myocardial rupture complicated acute myocardial infarction in a 50 year old man. Resuscitation was started immediately and he was treated with pericardiocentesis and a massive intravascular infusion of fluid. The torn area was plicated with Teflon felt and reinforced with an uninterrupted suture. The postoperative course was uncomplicated. This report points out the crucial importance of prompt...

Inadequate healing of myocardial infarction may contribute to local expansion of the infarct, frequently leading to chamber dilation, heart failure, or myocardial rupture. Experimental evidence in mouse models suggests that Factor XIII might play a key role in wound healing, and low persistent values lead to increased incidence of cardiac rupture following myocardial infarction. Here we would l...

OBJECTIVE To analyse the prodrome of acute myocardial infarction in relation to the plaque morphology underlying the infarct. DESIGN A retrospective investigation of the relation between rupture and erosion of coronary atheromatous plaques and the clinical characteristics of acute myocardial infarction. The coronary arteries of 100 patients who died from acute myocardial infarction were cut t...

Mechanical complications of myocardial infarction (MI) are often fatal. Little is known about endogenous factors that predispose to myocardial rupture after MI. Ectonucleoside triphosphate diphosphohydrolase (CD39) could be a critical mediator of propensity to myocardial rupture after MI due to its role in modulating inflammation and thrombosis. Using a model of permanent coronary artery ligati...

BACKGROUND Cardiac rupture is a rare but potentially lethal complication of acute myocardial infarction with ST-elevation (STEMI). Primary percutaneous coronary intervention (pPCI) is a preferable treatment method of acute STEMI. Reperfusion at vascular and myocardial levels may be the key parameters determining probability of cardiac rupture. AIM To analyse the relationship between reperfusi...

Ventricular rupture occurs in 10% of acute myocardial infarctions and is associated with significant mortality. We describe two cases of ventricular rupture post myocardial infarction who survived. We highlight salient points in their diagnosis and management and review the existing literature to determine what constitutes optimal management in these difficult cases.