Objective: The aim of our study was to investigate the association between salivary flow rate in diabetes mellitus and development coronary artery disease. Methodology: A cross-sectional executed Cardiology Department Civil Hospital Karachi. Unstimulated saliva collected 9 11 a.m. Participants were asked refrain from eating drinking for 1 hour before collection. They then instructed collect 5 m...

BACKGROUND There is growing evidence for a clinical benefit of primary percutaneous coronary intervention (PCI) compared with fibrinolysis; however, whether the treatment effect is consistent among patients with diabetes mellitus is unclear. We compared PCI with fibrinolysis for treatment of ST-segment elevation myocardial infarction in patients with diabetes mellitus. METHODS A pooled analys...

To the Editor: Nylen and colleagues reported that physical fitness, as represented by exercise capacity, reduces the risk of mortality in people with diabetes mellitus regardless of age. I compliment the authors on their excellent study. I would also like to mention that data were reported from a study of 609 people with diabetes mellitus with a mean age of 70 with no history of coronary artery...

BACKGROUND Rosiglitazone improves glycemic control for patients with type 2 diabetes mellitus, but there remains controversy regarding an observed association with cardiovascular hazard. The cardiovascular effects of rosiglitazone for patients with coronary artery disease remain unknown. METHODS AND RESULTS To examine any association between rosiglitazone use and cardiovascular events among p...

BACKGROUND The phenomenon of silent myocardial infarction is poorly understood. METHODS We aimed to evaluate the prevalence, extent, and independent predictors of silent myocardial infarction in 2 large independent cohorts of consecutive patients without a history of myocardial infarction referred for rest/stress myocardial perfusion single photon emission computed tomography. There were 1621...

BACKGROUND The Trial to Assess Chelation Therapy (TACT) showed clinical benefit of an EDTA-based infusion regimen in patients aged ≥50 years with prior myocardial infarction. Diabetes mellitus before enrollment was a prespecified subgroup. METHODS AND RESULTS Patients received 40 infusions of EDTA chelation or placebo. A total of 633 (37%) patients had diabetes mellitus (322 EDTA and 311 plac...

Patients with diabetes mellitus have worse outcomes after percutaneous coronary intervention than patients without diabetes mellitus. We compared the risk of stent thrombosis, myocardial infarction, death, and target lesion revascularization in diabetic and nondiabetic patients after implantation of drug-eluting stents or bare metal stents. In the Western Denmark Heart Registry, 12,347 consecut...

Background: Vitamin D deficiency is a global public health problem. linked to number of non skeletal major chronic diseases like cardiovascular disease.Objectives: To determine the frequency vitamin in patients presenting with ST segment elevated myocardial infarction. Methods: During study period, 150 fulfilling selection criteria elevation Myocardial infarction were included this study. A blo...