Right bundle branch block (RBBB) is usually considered almost unavoidable after repair of tetralogy of Fallot (TOF). By modifications of the standard technique, its frequency has been decreased to 32% in a series of 100 consecutive patients. These modifications are: (1) a very short right ventricular incision, avoiding the ventriculotomy-induced RBBB pattern; (2) an infundibular resection limit...

Right bundle branch block (RBBB) is usually considered almost unaviodable after repair of teralogy of Fallot (TOF). By modifications of the standard technique, its frequency has been decreased to 32% in a series of 1000 consecutive patients. These modifications are: (1) a very short right ventricular incision avoiding the ventriculotomy-induced RBBB pattern; (2) an infundibular resection limite...

BACKGROUND Muscular ventricular septal defects (VSD) are an important and difficult surgical problem. In the last few years a new alternative has emerged - possibility of VSD closure using percutaneous approach. AIM To present our experience in percutaneous closure of congenital muscular and one posttraumatic VSD. METHODS We treated 10 patients - 7 children (age 0.8-7 years) and 2 adults (4...

Congenital aneurysms of the muscular interventricular septum without ventricularseptal defect are extremely rare. We describe a five-month-old girl patient with congenital aneurysm, pathological ST changes and minimal right ventricular outflow tract obstruction. The electrocardiogram showed Wolf-Parkinson-White syndrome, pathological ST changes and combined ventricular hypertrophy criteria. The...

The course of the atrioventricular conducting tissues was studied in IO hearts having ventricular septal defects. Seven of the defects were in the membranous portion of the septum, and in these hearts the common atrioventricular bundle passed down the posterior edge of the defect and bifurcated on its inferior border. In 3 of these specimens the bundle deviated to the left side of the septum be...

OBJECTIVES The purpose of this study was to investigate the outcome in infants with hypoplastic left heart syndrome and intact atrial septum and to evaluate the relationship of atrial morphology, left atrial decompression pathway and lung histopathology to outcome. BACKGROUND In the hypoplastic left heart syndrome, severe restriction at the atrial level results in marked systemic hypoxemia af...

Anatomical considerations suggest the supraventricular crest (SC) is important for right ventricular free-wall to septum (RV FW-S) inward motion and may importantly influence overall (RV) function. The of approximation FW-S on RV function, implicitly importance SC, be judged from patients with repaired tetralogy Fallot (rToF), where components this muscular bridge are separated. functional para...

BACKGROUND AND PURPOSE The recent increase in the prevalence of ventricular septal defect (VSD) has been ascribed to the improved detection of small defects with echocardiography and the wider use of screening. The aim of this study was to determine the prevalence and timing of spontaneous closure of specific types of VSD in neonates using echocardiographic screening and follow-up. METHODS Tw...

Mammalian Tolloid-like 1 (mTLL-1) is an astacin-like metalloprotease, highly similar in domain structure to the morphogenetically important proteases bone morphogenetic protein-1 (BMP-1) and Drosophila Tolloid. To investigate possible roles for mTLL-1 in mammalian development, we have used gene targeting in ES cells to produce mice with a disrupted allele for the corresponding gene, Tll1. Homoz...

Ventricular septal defect (VSD) is the most common congenital heart malformation and can be detected during the prenatal and postnatal period, in childhood, and in adulthood. Spontaneous closure of VSD can be determined through a variety of methods-echocardiography, Doppler color flow imaging, angiography, auscultation, and cardiac catheterization-and can be proven by pathological evidence at n...