Muscular dystrophy is a hereditary and progressive degenerative disorder affecting skeletal muscles, and often-other organ systems (1). The real burden of muscular dystrophy in Malaysia is difficult to estimate, since the epidemiological data for each of muscular dystrophies and even for muscular dystrophies in collective are not available. There are not many researches focusing on muscular dys...

Parkinson’s disease (PD) is a neurodegenerative disease that disrupts the functionality and quality of life in persons affected by the disease. Motor symptoms associated with PD include resting tremor, rigidity, bradykinesia, diminished postural stability and decreased muscular strength [3]. The combination of aging, degenerative effects of the disease, and reduced physical activity often manif...

Spinal muscular atrophy (SMA) is a neuromuscular disorder characterized by degeneration of alpha motor neurons resulting in hypotonia, progressive muscular weakness and atrophy.30 Spinal muscular atrophy is one of the leading hereditary causes of infant mortality,31 it comprises the second most common fatal progressive diseases after cystic fibrosis.28 Spinal muscular atrophy is the most common...

The involvement of the sarcoglycan complex in the pathogenesis of muscular dystrophy is becoming increasingly clear. Sarcoglycan gene mutations lead to four forms of autosomal recessive limb-girdle muscular dystrophy. Recent progress has been made with the identification of novel mutations and their correlations with disease. Through this research, a better understanding the molecular pathogene...

Received Aug 29, 2017 Revised Oct 31, 2017 Accepted Nov 14, 2017 Muscular dystrophy is a rare genetic disorder that affects the muscular system which deteriorates the skeletal muscles and hinders locomotion. In the finding of genetic disorders such as Muscular dystrophy, the disease is identified based on mutations in the gene sequence. A new model is proposed for classifying the disease accura...

abstract bachground: the main objective of this study was to define the clinical changes of facial deformity in patients older than 5 years with congenital torticollis treated by proximal and distal sternocleidomastoid tenotomy. methods: we retrospectively evaluated fifteen patients who had had an open tenotomy of the sternal and clavicular and mastoid origins of the sternocleidomastoid muscle ...

Received Aug 29, 2017 Revised Oct 31, 2017 Accepted Nov 14, 2017 Muscular dystrophy is a rare genetic disorder that affects the muscular system which deteriorates the skeletal muscles and hinders locomotion. In the finding of genetic disorders such as Muscular dystrophy, the disease is identified based on mutations in the gene sequence. A new model is proposed for classifying the disease accura...

abstract objective autosomal recessive spinal muscular atrophy (sma) is, after cystic fibrosis, the second most common fatal monogenic disorder and the second most common hereditary neuromuscular disease after duchenne dystrophy. the disease is characterized by degeneration of anterior horn cells leading to progressive paralysis with muscular atrophy. depending on the clinical type (werdnig- ho...

Abstract Background Type 1 spinal muscular atrophy is a rare, progressive neuromuscular disease that caused by low levels of functional survival motor neuron (SMN) protein. Risdiplam an or...

OBJECTIVE To examine prospectively the association between muscular strength and mortality from all causes, cardiovascular disease, and cancer in men. DESIGN Prospective cohort study. SETTING Aerobics centre longitudinal study. PARTICIPANTS 8762 men aged 20-80. MAIN OUTCOME MEASURES All cause mortality up to 31 December 2003; muscular strength, quantified by combining one repetition max...