LL-37, an active form of human cathelicidin exhibits various effects on immunity and inflammation, such as induction inflammatory cells angiogenesis in addition to its antimicrobial activity. Involvement LL-37 the pathogenesis several skin diseases psoriasis rosacea has been described. To search for association other diseases, we focused scleroderma dermatomyositis. Previously, it shown that is...

Eleven patients with writer's cramp were studied during the performance of a series of writing and non-writing tasks. Their performance in the tasks and the intensity of contraction in the flexor and extensor muscles of the fingers and elbow (recorded electromyographically) were compared with the results from a group of matched normal controls. The patients showed highly significant increases i...

In order to clarify the abnormality in cortical motor preparation for voluntary muscle relaxation of the hand in patients with focal hand dystonia, Bereitschaftspotentials (BPs) preceding voluntary muscle contraction and relaxation were recorded in eight patients (three with simple writer's cramp and five with dystonic writer's cramp), and were compared with those from 10 normal subjects. Volun...

Motor imagery (MI) is the mental rehearsal of a motor act without overt movement. Using transcranial magnetic stimulation (TMS), we tested the effect of MI on corticospinal excitability in patients with writer's cramp. In 10 patients with writer's cramp and 10 healthy controls, we applied focal TMS over each primary motor area and recorded motor evoked potentials (MEPs) from contralateral hand ...

The study is aimed at investigating the occurrence of writers cramp in office workers, drawn from ten major offices of Kanpur to determine the nature and relationship of various emotional factors in the development of this disability. The observations on writers cramp cases were compared with a group of normal and diseased controls. Out of a surveyed population of 3,325 office workers, there we...

Four cases of muscle cramps, at a sports institute, are presented. Electric activity was increased in cramp due to overload. The influence of stretching, electro- and compression therapies on these increased Electromyographic (EMG) activities was studied. The registration was performed with an EMG-analyser combined with a recorder, using surface electrodes.

The cramp threshold frequency (CTF) is known to be positively correlated with the individual cramp susceptibility. Here we assessed CTF changes after two bouts of electrically induced muscle cramps (EIMCs). The EIMCs (6×5 sec) were unilaterally induced twice (separated by one week) in the gastrocnemius of an intervention group (n=8), while 5 participants served as control. The CTF increased fro...