Multifocal electroretinography (mfERG) is a valuable technique in assessing macular function in retinal disease objectively as it provides spatial information. Altered responses give an estimate of the extent of central retinal dysfunction. Fixation is known to be an important technical factor in mfERG recording. We present findings in a patient with asymptomatic intermittent exotropia that rei...

Multifocal electroretinography (mfERG) is a valuable technique in assessing macular function in retinal disease objectively as it provides spatial information. Altered responses give an estimate of the extent of central retinal dysfunction. Fixation is known to be an important technical factor in mfERG recording. We present findings in a patient with asymptomatic intermittent exotropia that rei...

PURPOSE To investigate changes in multifocal electroretinography (mfERG) parameters associated with high dose chloroquine therapy for treatment of malaria in the Amazonia region of Brazil. METHODS Forty-eight subjects who had received chloroquine treatment for single or multiple malaria infections with a cumulative dose ranging from 1,050 to 27,000mg were included. The control group consisted...

PURPOSE To correlate and compare retinal function measured using multifocal electroretinography (mfERG) with microperimetry in intermediate age-related macular degeneration (AMD). METHODS Sixty AMD participants underwent multifocal electroretinography (mfERG) and microperimetry testing in one eye, and 44 control participants were included to provide normative values for each test. Thirteen he...

OBJECTIVES To compare different screening procedures for hydroxychloroquine sulfate (Plaquenil) toxicity at different stages of damage. METHODS Ten patients were studied using 10-2 automated fields, multifocal electroretinography, spectral domain optical coherence tomography (SD-OCT), and fundus autofluorescence. RESULTS All 10 patients used hydroxychloroquine for more than 6 years, and tho...

PURPOSE Detailed morphologic and functional evaluation of adult vitelliform macular dystrophy (AVMD). METHODS The records of 61 consecutive AVMD patients (inclusion criterion: vitelliform lesion smaller than one disk diameter at least in one eye) were evaluated retrospectively regarding visual acuity, color vision, perimetry, retinal pigment epithelium (RPE) autofluorescence, fluorescein angi...

PURPOSE To assess the applicability of multifocal electroretinograms (mfERGs) for evaluation of function in this small-eyed animal with a rod-dominant retina that is often used to model retinal diseases. METHODS Noninvasive monocular mfERGs were recorded in anesthetized albino (Sprague-Dawley) and pigmented (Long Evans) rats. Achromatic stimuli subtending a 49 degrees by 53 degrees field cons...