نتایج جستجو برای: mucus

تعداد نتایج: 10619  

Amégnona Agbonon Kodjo A. Aklikokou Kossi Metowogo, Kwashie Eklu-Gadegbeku Messanvi Gbeassor

Aloe buettneri A. Berger is commonly used in traditional Togolese medicine to treat inflammatory and gastric ulcers. The present study examined the gastro-protection effect of the hydro-alcoholic extract of A. buettneri on mucus production and gastric pH. A gastric ulcer is induced by ethanol 95° alone (1 ml/kg body weight), after pre-treatment with indomethacin (300 mg/kg) or by utilising L-NA...

2011
Ying-Ying Wang Samuel K. Lai Conan So Craig Schneider Richard Cone Justin Hanes

Mucus secretions typically protect exposed surfaces of the eyes and respiratory, gastrointestinal and female reproductive tracts from foreign entities, including pathogens and environmental ultrafine particles. We hypothesized that excess exposure to some foreign particles, however, may cause disruption of the mucus barrier. Many synthetic nanoparticles are likely to be mucoadhesive due to hydr...

2011
Victor Stalin Raj Guillaume Fournier Krzysztof Rakus Maygane Ronsmans Ping Ouyang Benjamin Michel Cédric Delforges Bérénice Costes Frédéric Farnir Baptiste Leroy Ruddy Wattiez Charles Melard Jan Mast François Lieffrig Alain Vanderplasschen

Cyprinid herpesvirus 3 (CyHV-3) is the aetiological agent of a mortal and highly contagious disease in common and koi carp. The skin is the major portal of entry of CyHV-3 in carp after immersion in water containing the virus. In the present study, we used in vivo bioluminescence imaging to investigate the effect of skin mucus removal and skin epidermis lesion on CyHV-3 entry. Physical treatmen...

Journal: :Respiratory care 2011
Stanislav Tatkov Rodger J Pack

BACKGROUND The efficacy of symmetrical-waveform high-frequency oscillating (HFO) air flow for airway secretion clearance is controversial and debated in the literature. METHODS We conducted in vitro experiments with ovine tracheae to investigate the effects of symmetrical-waveform HFO on tracheal transport of artificial mucus. We mounted each trachea as an intact tube, with a 15(o) head-down ...

Journal: :The European respiratory journal 1992
S Girod J M Zahm C Plotkowski G Beck E Puchelle

The respiratory mucus is a very complex biological material, which possesses both flow and deformation rheological properties, characterized by non-linear and time-dependent viscoelasticity and physical properties of adhesiveness and wettability. Viscosity and elasticity are directly involved in the transport capacity of mucus, whereas wettability and adhesiveness contribute to the optimal inte...

2013
Anne-Claire Groo Patrick Saulnier Jean-Christophe Gimel Julien Gravier Caroline Ailhas Jean-Pierre Benoit Frederic Lagarce

The bioavailability of paclitaxel (Ptx) has previously been improved via its encapsulation in lipid nanocapsules (LNCs). In this work, the interactions between LNCs and intestinal mucus are studied because they are viewed as an important barrier to successful oral delivery. The rheological properties of different batches of pig intestinal mucus were studied under different conditions (the effec...

2014
David B. Hill Paula A. Vasquez John Mellnik Scott A. McKinley Aaron Vose Frank Mu Ashley G. Henderson Scott H. Donaldson Neil E. Alexis Richard C. Boucher M. Gregory Forest

In human airways diseases, including cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD), host defense is compromised and airways inflammation and infection often result. Mucus clearance and trapping of inhaled pathogens constitute key elements of host defense. Clearance rates are governed by mucus viscous and elastic moduli at physiological driving frequencies, whereas transp...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
André Schütte Anna Ermund Christoph Becker-Pauly Malin E V Johansson Ana M Rodriguez-Pineiro Fredrik Bäckhed Stefan Müller Daniel Lottaz Judith S Bond Gunnar C Hansson

The mucus that covers and protects the epithelium of the intestine is built around its major structural component, the gel-forming MUC2 mucin. The gel-forming mucins have traditionally been assumed to be secreted as nonattached. The colon has a two-layered mucus system where the inner mucus is attached to the epithelium, whereas the small intestine normally has a nonattached mucus. However, the...

Journal: :The European respiratory journal 1993
S Girod de Bentzmann D Pierrot C Fuchey J M Zahm J L Morançais E Puchelle

We have previously shown that a decreased level of phosphatidylglycerol in cystic fibrosis (CF) respiratory mucus is partly responsible for its marked adhesiveness and stickiness, which impair mucus transport, and that distearoyl phosphatidylglycerol (DSPG) was the most efficient form of phosphatidylglycerol in the enhancement of respiratory mucus clearance. The aim of our study was to analyse ...

2016
W. J. Weigand A. Messmore D. D. Deheyn A. Morales-Sanz D. L. Blair J. S. Urbach R. M. Robertson-Anderson

We characterize the scale-dependent rheological properties of mucus from the Chaetopterus sea annelid and determine the intrinsic lengthscales controlling distinct rheological and structural regimes. The mucus produced by this ubiquitous filter feeder serves a host of roles including filtration, protection and trapping nutrients. The ease of clean mucus extraction coupled with similarities to h...

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