safety and beneficence of farm animal nutrition plays a great role in their healthy life which in turn have impact on human nutrition via diary or meat products. assessing safety and beneficence of vicia varibilis freyn and sint. which is chosen intrinsically by domesticated animals of kohgiluyehand boyerahmad iranis the aim of the present work. our results not only show no cytotoxic activity i...

objective: achillea is a traditional medicinal herb which contains different phenol and flavonoid compounds that are responsible for achillea pharmacological effects. we aimed to determine phenol and flavonoid contents, besides antioxidant activities of different extracts from achillea eriophoraa (a. eriophora) dc. and achillea biebersteinii (a. biebersteinii) afan. (endemic species in iran) an...

medicinal plants have been investigated for possible anti-cancer effects. the aim of the present study was to examine the cytotoxic activity of several medicinal plants on different tumor cell lines. 11 selected plant species which have been used in folkloric prescriptions were collected from different sites of hamedan district of iran. the methanolic extracts of the plants were prepared and th...

cancer is one of the main causes of mortality in the world which appears by the effect of enviromental physico-chemical mutagen and carcinogen agents. the identification of new cytotoxic drugs with low side effects on immune system has developed as important area in new studies of immunopharmacology. thymoquinone (tq), derived from the medicinal spice nigella sativa (also called black cumin) ex...

aim : in this paper effect of combinational usage of calprotectin and etoposide on ags cell line is studied. background : application of combined toxic agents such as etoposide and cicplatin are commonly used for chemotherapy purposes. as a matter of fact, calprotectin and etoposide were both applied on human gastric adenocarcinoma cell line (ags) as antitumor agents. both calprotectin and etop...

background: the extensive use of different nanoparticles has raised great concerns about their occupational and biological safety. objective: the aim of this study was to evaluate the cytotoxic effect of zinc oxide nanoparticles (zno nps) on viability of spermatozoa. materials and methods: semen samples were obtained from 15 healthy persons, and were analyzed using who guidelines. each semen sa...

objectives the current study aimed to investigate the immunostimulatory effects of the aqueous extract of heracleum persicum on mouse peritoneal macrophages. background the immune system provides protection against infectious diseases that are caused by various microorganisms, in particular pathogenic fungi. utilization of herbal immunostimulants is one solution to improve the immunity of human...

phlomis lanceolata is a medicinal plant that has long been used to treat various conditions such as diabetes, gastric ulcer, hemorrhoids, inflammation and wounds. as most of phlomis species have shown cytotoxic activity against proliferation of different cell lines, a biological investigation of p. lanceolata was carried out in this study. the aim of this study was to find out the in vitro cyto...

background and objectives: colorectal cancer is the third most common cancer and a major cause of morbidity globally. hepatocellular carcinoma is a leading cause of death in the world. about 80% of all anticancer drugs are somehow related to natural products. one of the most important of these natural compounds is curcumin, the main component of turmeric that has a wide range of pharmacological...

background: during the past few years, hesa-a, a herbal-marine mixture, has been used to treat cancer as an alternative medicine in iran. however, weight of the evidence is not sufficient to accept or refuse the use of this compound as a cytotoxic drug. we investigated the selective anticancer effects of hesa-a on breast, prostate, colon, and glioblastoma multiforme (gbm) neoplastic cell lines....