The antiviral activity of total flavonoid extracts from Selaginella moellendorffii Hieron and its main constituents amentoflavone were investigated against coxsackie virus B3 (CVB3). When added during or after viral infection, the extracts and amentoflavone prevented the cytopathic effect (CPE) of CVB3, as demonstrated in a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) col...

PURPOSE To evaluate the protective effects of epigallocatechin gallate (EGCG) against UV irradiation of cultured human lens epithelial cells. METHODS We irradiated cultured human lens epithelial cells with a 30-second pulse from a UV lamp with an irradiance of 0.6 mW/cm2. Five minutes and 1 hour after UV irradiation, we administered 0, 5, 10, 15, 25, 50, or 100 uM EGCG. The cell number was me...

background: norepinephrine plays a trophic role in the control of cell replication and differentiation in target cells that express adrenergic receptors. methods: in this study, we have tested the influence of infraphysiological, physiological and supraphysiological concentrations (0.0001 nm, 1 nm, 10000 nm) of human norepinephrine on the proliferation of breast cancer cells (human breast adeno...

Abstract Background Ethnobotanical studies on plants and their active compounds take a great interest in traditional medicine. After pharmacological toxicological studies, there will be possibility to used therapy. This study aimed examine the vitro antioxidant cytotoxic activity of methanol extracts Arbutus andrachne L. Euphorbia rigida M.Bieb. 10, 25, 50, 75, 100 150 µg mL −1 concentrations A...

In the present study, tin nanoparticles were green-synthesized using aqueous extract of Foeniculum vulgare leaf extract. The synthesized SnNPs (tin nanoparticles) characterized by analytical techniques including EDX (energy dispersive X-ray), FE-SEM (field emission scanning electron microscopy), XRD (X-ray diffraction), UV–vis and FT-IR (Fourier transform-infrared). cytotoxicity activity was ev...

One of the primary goals antiviral research in recent decades has been biosynthesis new agents. The large number bioactive agents extracted from microbial isolates led to building connections between products through screening. Using a genotype 4 plasmid, extract fraction Pseudomonas oleovorans evaluated against HCV Hepatitis C cell culture. cytotoxicity assay using MTT [3-(4, 5-dimethylthiazol...

BACKGROUND The chromogenic assay based on MTT bioreduction was adapted to Proteus mirabilis viability estimations. We primarily intended to use the assay for the evaluation of novel antimicrobial compounds, including structures with possible permeabilizing activity. Therefore, the influence of basic permeabilizing agents like Triton X-100 and EDTA upon the MTT assay was studied. METHODS 3-(4,...

Background: Norepinephrine plays a trophic role in the control of cell replication and differentiation in target cells that express adrenergic receptors. Methods: In this study, we have tested the influence of infraphysiological, physiological and supraphysiological concentrations (0.0001 nM, 1 nM, 10000 nM) of human norepinephrine on the proliferation of breast cancer cells (human breast adeno...

Calotropis gigantea has been known to produce bioactive secondary metabolites with antiproliferative activities against cancer cells. Herein, we extracted the using ethyl acetate from its root bark and further tested P388 murine leukemia cell lines. The subfractions extract was obtained Vacuum Liquid Column Chromatography (VLCC), followed by Gravity (GCC). subfraction C2 D1 were identified cont...

Metallic nanoparticles are interesting areas of research due to their unique properties which can be advantageous for producing smart products. Silver (AgNPs) remarkably used in pharmaceutical industry because strong biological activities. The aim the present study was investigate cytotoxicity and wound healing capacity biologically prepared silver via green synthesis route. Cytotoxicity biogen...