to eliminate microorganisms that are responsible for pulpal and periapical infections and to prevent reinfection of the root canal system an effective chemomechanical preparation by irrigants with sustained antimicrobial activity is beneficial. hereby, we evaluated the residual antibacterial activity of mtad after canal obturation at different time intervals.a total of 120 human single-canalled...

1Professor, Department of Conservative Dentistry & Endodontics, Sree Sai Dental College and Research Institute, Srikakulam, Andhra Pradesh, India; 2Professor, Department of Conservative Dentistry & Endodontics, A J Shetty Dental College Mangalore, Karnataka, India; 3Reader, Department of Conservative Dentistry & Endodontics, Maitri College of Dentistry & Research Centre, Anjora, Chhattisgarh, I...

Amongst the bacterial species which most often cause endodontic failures, Enterococcus faecalis is the most important. This study compared the effectiveness of sodium hypochlorite and two new generation antibiotic-based endodontic irrigants, Tetraclean and MTAD. By means of an in vitro agar dilution assay, we show that both Tetraclean and MTAD are 100% effective against 54 clinical isolates at ...

Introduction: Historically, countless compounds in aqueous solution have been suggested as root canal irrigants. MTAD shows promise as an endodontic irrigant but there are very few studies comparing its antimicrobial effectiveness with NaOCl and Chlorhexidine. Objectives: To compare the antibacterial efficiency of MTAD, 2.5% Sodium Hypochlorite and 2% Chlorhexidine root canal irrigants against ...

BACKGROUND The most important and demanding aspect of endodontic therapy is considered to be cleaning and shaping. Irrigation is considered a vital adjunct to instrumentation of the root canal for canal debridement. Until date, there is no single solution that simultaneously removes the smear layer and disinfects the entire root canal system. Thus, this in vitro study was designed to evaluate t...

INTRODUCTION The production of smear layer during canal instrumentation is thought to increase coronal microleakage even after canal obturation. Previous studies have shown that the type of irrigant does not necessarily affect the seal of the obturation. Our study aimed to evaluate the effect of three irrigation solutions (MTAD, citric acid and EDTA/NaOCl) on the coronal microleakage of root ca...

INTRODUCTION This study compared the efficacy of BioPure MTAD (Dentsply Tulsa, Tulsa, OK), 17% EDTA, and 42% citric acid in endodontic smear layer removal and degree of erosion in the apical third of endodontic canals. METHODS Ninety-six extracted single-rooted human teeth were randomized into four groups (n = 24) and instrumented using System GT nickel-titanium rotary instruments (Dentsply T...

objective: biopure® mtad (dentsply tulsa dental, usa) has been developed as a final irrigant following root canal shaping to remove intracanal smear layer. many of the unique properties of mtad potentially transfer to the conditioning process of tooth roots during periodontal therapy. the aim of this ex vivo study was to evaluate the effect of mtad on the removal of smear layer from root surfac...

Context Human dentin powder (HD), bovine serum albumin (BSA) and endotoxin (LPS) may affect the antimicrobial activity of irrigating solutions. Aim To evaluate the inhibitory effect of HD powder, BSA, and LPS on the antibacterial activity of 0.5%, 1%, 2.5%, and 5% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX) gel, BioPure mixture of tetracycline, citric acid, and detergent (MTAD), and Q...

INTRODUCTION The aim of this study was to compare the smear layer removal efficacies of 3% sodium hypochlorite (NaOCl), 17% Ethylenediaminetetraacetic acid (EDTA), SmearClear and BioPure MTAD using a common irrigation protocol. MATERIALS AND METHODS Fifty freshly extracted human single rooted maxillary and mandibular teeth were prepared by a ProTaper rotary system up to an apical preparation ...