INTRODUCTION Metabolic syndrome (MS), which is connected with enlarged cardiovascular risk, is common in patients with OSAS. The aim of the study was to estimate the prevalence of MS in patients with OSAS according to two definitions of MS (criteria from NCEP-ATP III from 2001 versus criteria from IDF 2005). MATERIAL AND METHODS Materials consisted of 155 males and 18 females with OSAS (mean ...

The transcriptional activity of RNA polymerase II (Pol II) is a dynamic process and therefore measuring the kinetics of the transcriptional process in vivo is of importance. Pol II kinetics have been measured using biochemical or molecular methods. In recent years, with the development of new visualization methods, it has become possible to follow transcription as it occurs in real time in sing...

In a field study on the efficiency of dune recharge for drinking water production, bacteriophage MS2 was shown to be removed 8 log(10) by passage through the dune sand. The question of whether pathogenic viruses would be removed as much as MS2 was studied by comparing complete breakthrough curves of MS2 with those of the human viruses Coxsackievirus B4 (CB4) and Poliovirus 1 (PV1) in laboratory...

Adenoviruses, the most UV resistant microorganism currently known, are posing concerns in UV treated drinking water. To reduce the risk from adenovirus infection, combination processes of UV and chlorination are attractive. Bacteriophage MS2 and adenovirus 5 (AdV5) were used in this study, and inactivated by low-pressure UV (LPUV) lamp, chlorination, sequential processes (UV-Cl2 and Cl2-UV) and...

In this study, we characterized two blocks of minisatellites in the 5' upstream region of the BORIS gene (BORIS-MS1, -MS2). BORIS-MS2 was found to be polymorphic; therefore, this locus could be useful as a marker for DNA fingerprinting. We assessed the association between BORIS-MS2 and breast cancer by a case-control study with 428 controls and 793 breast cancers cases. Rare alleles in the youn...

Ultraviolet irradiation or nitrosoguanidine treatment of Escherichia coli K-12 strain JE3100 (F'(8)/fla pil) led to the isolation of six mutants defective in F pili function. The defects were shown to be caused by mutations in the F factor. The mutants retained conjugal fertility, although they were less efficient than parental F'(8) strain, and continued to synthesize F pili. Three of the muta...

All samples were analyzed on a Thermo Scientific Q ExactiveTM. Two acquisition modes were used. A full MS scan at 35,000 resolution with positive and negative switching. The other acquisition mode was a full MS at 70,000 resolution followed by data-dependent MS2 in both positive and negative polarities. An inclusion list for all the respective batches was included in the full MS data-dependent ...

Quantitative analysis of discovery-based proteomic workflows now relies on high-throughput large-scale methods for identification and quantitation of proteins and post-translational modifications. Advancements in label-free quantitative techniques, using either data-dependent or data-independent mass spectrometric acquisitions, have coincided with improved instrumentation featuring greater prec...