Mammalian Ste20-like proline/alanine-rich kinase (SPAK) and oxidative stress-responsive 1 (OSR1) kinases phosphorylate and regulate cation-coupled Cl(-) cotransporter activity in response to cell volume changes. SPAK and OSR1 are activated via phosphorylation by upstream with-no-lysine (WNK) kinases. In Caenorhabditis elegans, the SPAK/OSR1 ortholog germinal center kinase (GCK)-3 binds to and r...

The Generalized Minimum Residual (GMRES) method is a popular Krylov subspace projection method for solving a nonsymmetric linear system of equations. On modern computers, communication is becoming increasingly expensive compared to arithmetic operations, and a communication-avoiding variant (CA-GMRES) may improve the performance of GMRES. To further enhance the performance of CAGMRES, in this p...

BACKGROUND Current chemotherapy for Chagas disease is unsatisfactory due to its limited efficacy, particularly in the chronic phase, with frequent side effects that can lead to treatment discontinuation. Combined therapy is envisioned as an ideal approach since it may improve treatment efficacy whilst decreasing toxicity and the likelihood of resistance development. We evaluated the efficacy of...

Kajian ini bertujuan untuk mengenal pasti cabaran yang dihadapi oleh guru dan Murid Pendidikan Khas (MPK) Penglihatan menggunakan alat bantu teknologi dalam pengajaran pembelajaran. kuantitatif borang soal selidik sebagai instrumen mengumpul data. Seramai 100 orang mengajar MPK dipilih secara rawak sampel kajian. Data kajian telah dianalisis dengan perisian Statistical Package for the Social Sc...

Several modified terpolymer polyketones (MPK) with N-substituted pyrrole moieties in the main chain and quaternized amine side group were synthesized for use as anion exchange membranes fuel cells. The carried by SiO2 nanoparticles through surface functionalization (Si–N), which added to enhance their overall properties. On increasing amount of silica from 10% 60% wt/of MPK, there was an increa...

In the germline of Caenorhabditis elegans hermaphrodites, meiotic cell cycle progression occurs in spatially restricted regions. Immediately after leaving the distal mitotic region, germ cells enter meiosis and thereafter remain in the pachytene stage of first meiotic prophase for an extended period. At the dorsoventral gonadal flexure, germ cells exit pachytene and subsequently become arrested...

Suspension cultured cells of the liverwort Marchantia paleacea var. diptera (MpK) were investigated to clarify the relationship between morphogenesis and the mode of utilization of nitrogen sources in different media. MpK cells grew vigorously in a Murashige and Skoog's liquid medium with 4% glucose in the light condition. Thallus regeneration from cultured cells occurred in culture medium with...

We study capital misallocation within and across 10 African countries using the World Bank Enterprise Surveys. First, we compare the extent of misallocation among firms within countries. We document high variation in firms’ marginal product of capital (MPK), implying that countries could produce significantly more with the same aggregate capital stock if capital were allocated optimally. Such v...