Peripheral nerve disorders are important late complications of diabetes mellitus. Polyneuropathy, which may involve varying proportions of sensory, motor, and autonomic fibers, is considered the consequence of metabolic derangements that result from chronic hyperglycemia. Symmetrical proximal motor neuropathy ("diabetic amyotrophy") also may have a metabolic basis. Mononeuropathies in diabetes ...

Hereditary neuropathy with liability to pressure palsies (HNPP) is a dominantly inherited disorder that presents as recurrent mononeuropathies precipitated by apparently trivial traumas. The presence of a deletion in 17p11.2 was analysed in 13 Finnish families with HNPP. The deletion was found in all patients who were neurologically and neurophysiologically confirmed to have HNPP. In the proble...

OBJECTIVE To evaluate the necessity of neuroimaging in patients with acute, isolated ocular motor mononeuropathies. METHODS A prospective case series evaluating diagnostic technology results in 93 patients older than 50 years with acute isolated mononeuropathies was performed. Patients were included in the study if they had new-onset diplopia with an isolated cranial neuropathy (cranial nerve...

BACKGROUND The prevalence of hepatitis C virus (HCV) infection has been estimated at 43 to 84% in patients with essential mixed cryoglobulinaemia in recent large series. Some of these cases have been successfully treated with interferon-alpha. The objective was to evaluate the prevalence and the possible role of HCV infection in essential mixed cryoglobulinaemia. METHODS Fifteen patients (eig...

Fifty four patients with peripheral nerve syndromes were seen during a 15 month period in a population of about 1500 HIV infected patients at all stages of the disease. Distal symmetrical peripheral neuropathies were seen in 38 of the 54 patients, (11.5% of AIDS patients) and could be distinguished into two forms. The most common (n = 25) was a painful peripheral neuropathy during AIDS, which i...

Background: A database which documents the diagnosis of neuromuscular patients is useful for determining types referred to academic centers and identifying participants clinical trials other studies. The ICD-9 or ICD-10 numeric systems are insufficiently detailed this purpose. Objective: To develop a diagnoses Methods: We developed diagnostic coding system diseases called DEMAND: Database Evalu...

Meralgia paresthetica is a mononeuropathy which occurs as result of lateral femoral cutaneous nerve being under pressure at groin level; with numbness, pains and needles, and pain at external collateral and anterior thigh and inguinal region. Its treatment is conservative and surgical. In our study, we intended to present our clinical evaluation as result of transforaminal epidural steroid appl...

OBJECTIVE To determine which proposed risk factor, work activity (industrial v clerical), body mass index (BMI), or other demographic factors had the most influence on the prevalence of median mononeuropathy at the wrist, and if there was an interaction between the risk factors. METHODS This was a cross sectional study of active workers at five different worksites; four were industrial sites ...

Factors that predispose patients to ulnar mononeuropathy at the elbow (UME) are poorly defined. We compared 112 electrodiagnostic reports which met criteria for definite or probable UME to 104 reports which excluded UME. Male gender was strongly associated with definite (OR = 6.9, 95% CI = 2.4-20.4; P < 0.001) and all UME (OR = 2.2, 95% CI = 1.2-4.1; P = 0.010) after controlling for age and bod...