Three new compounds, including two phenylacetic acid derivatives, monaspilosin (1) and monaspiloindole (2), and one pyranoindole alkaloid, monaspyranoindole (3), were isolated from the EtOAc-soluble fraction of the MeOH extract of the mycelia of Monascus pilosus BCRC 38072. Twelve known compounds were also obtained in this study. The structures were elucidated by 1D and 2D NMR spectroscopy and ...

The present study investigated the effects of agitation speed, N (200, 500, 600 or 700 rpm), and dissolved oxygen concentration, C (120, >70, 70, 60, 10 or 10%), on red pigment and citrinin production by Monascus purpureus ATCC 36928, cultivated in liquid medium by a batch process. The gas flow rate was the same for all runs with C controlled by means of the incoming gas composition control (ai...

I.緒言 紅麹菌の生産する紅麹色素は,食品の着色料,着香 料,保存剤として幅広く利用されており,抗菌作用 (Wong et al., 1977, Wong et al., 1981, Martinkova et al., 1999),発癌予防効果(安川等,1991),抗炎症作 用(Yasukawa et al., 1994, 1996)などの生理活性作 用を有することが知られている.穀類に紅麹菌を生育 させた紅麹には,コレステロール生合成阻害活性を有 す る モ ナ コ リ ン K(Endo et al, 1979, 1980, 1985a, 1985b)や血圧降下作用を有するγ-アミノ酪酸(辻等, 1992a,1992b,1992c,1992d,1992e,1993,久代等, 1996)などの生理活性物質が含まれていることが報告 されている.近年,モナコリン K には骨形成たんぱ ...

Monascus has been used for thousands of years. In China, Monascus has been widely used as a natural food-coloring agent for many kinds of foods. The metabolites of Monascus species, specifically, monacolin K, gamma-aminobutyric acid, and dimerumic acid, have been proven to have cholesterol-lowering, blood pressure-lowering, and antioxidant effects. Nowadays, the public has recognized the import...

Citrinin is a mycotoxin, which is produced by fungi belonging to the genus Monascus, known in biotechnology as producers of azaphilone pigments. The relation between biosynthesis of these secondary metabolites was investigated in different species of the genus Monascus in batch-culture at the following cultivation conditions: T = 28 degrees C, agitation 220 rpm, and a medium, which induce citri...

Ochratoxin A (OTA) is a very important mycotoxin, and its research is focused right now on the new findings of OTA, like being a complete carcinogen, information about OTA producers and new exposure sources of OTA. Citrinin (CIT) is another important mycotoxin, too, and its research turns towards nephrotoxicity. Both additive and synergistic effects have been described in combination with OTA. ...

Solid substrate fermentation (SSF) of Monascus purpureus on rice is a promising new technology for obtaining natural pigments. However, before attempts can be made at maximizing pigment yield, all significant macroscopic compounds should be assayed. Here, Monascus purpureus has been grown on rice in batch mode, and the evolution of the main components, biomass, residual rice, O(2), CO(2), ethan...

BACKGROUND Monascus pigments are promising sources for food and medicine due to their natural food-coloring functions and pharmaceutical values. The innovative technology of extractive fermentation is used to promote pigment productivity, but reports of pigment trans-membrane secretion mechanism are rare. In this study, tracking of pigment accumulation and secretion in extractive fermentation o...

in present study, two species of hyphomycetes fungi including, cephaliophora tropica (in soil), and monascus pilosus (on corn silage) are reported for the first time to iranian mycobiota. descriptions of these species have been provided with morphological characteristics and its rdna sequence analyses.in present study, two species of hyphomycetes fungi including, cephaliophora tropica (in soil)...