نتایج جستجو برای: molecular physiology
تعداد نتایج: 713032 فیلتر نتایج به سال:
P2X receptors are membrane ion channels that open in response to the binding of extracellular ATP. Seven genes in vertebrates encode P2X receptor subunits, which are 40-50% identical in amino acid sequence. Each subunit has two transmembrane domains, separated by an extracellular domain (approximately 280 amino acids). Channels form as multimers of several subunits. Homomeric P2X1, P2X2, P2X3, ...
To the Editor: In their review article on water balance, Knepper et al. (April 2 issue)1 discuss water channels (aquaporins) in renal tubular cells. They omit mention of the critical role played by aquaporin-1 in microvascular endothelia. In the renal microvasculature, endothelial aquaporin-1 mediates the osmotic water efflux across descending vasa recta and is required for regulation of medull...
The heart is a rhythmic electromechanical pump, the functioning of which depends on action potential generation and propagation, followed by relaxation and a period of refractoriness until the next impulse is generated. Myocardial action potentials reflect the sequential activation and inactivation of inward (Na(+) and Ca(2+)) and outward (K(+)) current carrying ion channels. In different regio...
Copenhagen Muscle Research Centre, *Dep. of Human Physiology, Inst. of Exercise and Sport Sciences, University of Copenhagen, Inst. of Molecular Biology and Physiology, University of Copenhagen, Dep. for Molecular Muscle Biology, Rigshospitalet, Copenhagen, Denmark. Institut Cochin, INSERM, CNRS, Rene Descartes University, Department of Genetic, Development and Molecular Pathology, Paris, Franc...
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