multiple sclerosis is an autoimmune cns-disease characterized by inflammatory neurodegenerative events occurring with de- and remyelination. recent evidence show that demyelinated neurons are less excitable than myelinated ones while at early stages of remyelination these neurons seem to be hyperexcitable. the latter is a transitory condition that, very likely, leads to impaired neuronal networ...

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background: numerous studies have assessed risk factors for multiple sclerosis (ms), but regarded to paradoxical results & specific ethnical- cultural circumstances in ahvaz, as a city in iran, this case-control study was aimed to assess some factors related to lifestyle (consumption & exposure with cigarette smoking, duration & surface of sun light exposure, exposure to pets and farm animals) ...

background: due to many physical and mental disorders that occur in multiple sclerosis patients, identifying the factors affecting coping based on the experiences of patients using qualitative study is essential to improve their quality of life. this study was conducted to explore the antecedents of coping with the disease in patients with multiple sclerosis. methods: this is a qualitative stud...

MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that regulate protein expression through sequencespecific post-transcriptional gene silencing. They are produced as long primary transcripts (pri-miRNAs) and processed inside the nucleus by the RNase III “Drosha” to liberate the ~70-nucleotide miRNA precursor hairpins (pre-miRNA). After being exported to the cytoplasm, the second RNAse II...

Background & Aims: Substance abuse may have different effects on multiple sclerosis. Till now, studies on substance abuse and its correlation with psychopathology, type and severity of multiple sclerosis are limited. We conducted this study to evaluate the psychopathology of patients with multiple sclerosis with and without substance abuse. Methods: In this case-control, cross-sectional study p...

how to cite this article: inaloo s, haghbin s. multiple sclerosis in children. iran j child neurol. 2013 spring;7(2):1-10.   multiple sclerosis (ms) is the most important immune-mediated demyelinated disease of human which is typically the disease of young adults. a total of 4% to 5% of ms population are pediatric. pediatric ms is defined as the appearance of ms before the age of sixteen. about...

Multiple Sclerosis (MS) is a prevalent neurological and non-traumatic disease which is most common in young and adult women. Multiple Sclerosis is a disabling disease can affect various aspects of life. Studies have reported that complement and alternative treatments can have positive effects on people with MS. Exercise presents an important behavioral approach for counteracting the declines in...