نتایج جستجو برای: mirn103 microrna
تعداد نتایج: 37395 فیلتر نتایج به سال:
objective: different signaling pathways have been identified that are involved in the cellular response to opiates. the mitogen-activated protein kinase pathway is one of the most important signaling pathways underlying the neuronal response to opiates. micrornas (mirnas) are considered to be post-transcriptional regulators of gene expression with paramount significance, which plays key roles i...
Drug resistance is the leading cause of death in prostate cancer patients. Therefore, exploring mechanism underlying drug and identifying novel therapeutic targets are urgently needed. Long non-coding ribonucleic acid disrupted renal carcinoma 3 acts as a tumor suppressor gene several types. However, to date, no study has investigated biological function long cancer. Gene expression was detecte...
زمینه و هدف: تغییر بیان microrna (mirna) ها مشخصه عمومی بسیاری از بدخیمی ها می باشد. تغییر بیان و یا عملکرد پروتئین های مسئول بیوژنز mirna ها، از مکانیسم های پایه ای مولکولی در تغییر بیان mirnaها است. اکسپورتین 5 (xpo5) نقش رابط بین مرحله هسته ای و سیتوپلاسمی مسیر بیوژنز را برعهده داشته که تا کنون ارتباط آن با چندین سرطان گزارش شده است اما نقش این ژن به خوبی در سرطان پستان مورد پژوهش قرار نگرفت...
p 61: microrna as a therapeutic tool to prevent blood brain barrier dysfunction in neuroinflammation
endothelial cells present in brain are unique and differ from other peripheral tissues in a number of ways, which ensures specific brain endothelial barrier properties. endothelial dysfunction is the earliest event in the initiation of vascular damage caused by inflammation. various micrornas (mirna) have been discovered in different cellular components of the blood bran barrier (bbb). mirnas a...
micrornas are highly conserved small non-coding regulatory rnas that involve in post transcriptional regulating of gene expression during different cellular mechanisms. aberration of mir-218 expression during tumorigenesis of different solid tumors has been reported by numerous studies. in current systematic review article, by using the terms “mir-218” and “cancer” we first searched for english...
Glioma is the most frequent primary intracranial tumor worldwide. Dexmedetomidine an efficient anesthetic used in surgery and has impact on glioma. Yet, mechanism of dexmedetomidine biological characteristics glioma cells unknown. Circ_BRAF, microRNA-381-3p thrombospondin 2 was detected via quantitative reverse transcription-polymer chine reaction. Proliferation detection conducted using 3-(4,5...
مقدمه و هدف: سرطان مری یکی از کشنده ترین سرطان ها در سرتاسر جهان می باشد. استان گلستان یکی از بالاترین نرخ های شیوع سرطان سلول های سنگفرشی مری در جهان را دارد. microrna ها یک گروه از rna های غیر کد کننده هستند که بیان تنظیم نشده آن ها با بسیاری از سرطان ها در ارتباط است. خوشه mir-302-367 شامل نه microrna است، که بیان آن ها محدود به سلول های بنیادی جنینی و سلول های کارسینومای جنینی است و از تنظی...
MicroRNAs form a class of small non-coding RNA molecules. With only 21-23 nucleutide in length, they have an important role in gene expression. These molecules bind to their target mRNA molecules and repress the protein expression via mRNA degradation or blocking the translation machine of the cell. From the advent of molecular biology microRNA molecules were out of focus, however huge amount o...
micrornas (mirnas) represent a class of small non-coding rna molecules that regulate gene expression at the post-transcriptional level. they play a crucial role in diverse cellular pathways. ionizing radiation (ir) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. recently it has been discovered that mi...
UNLABELLED MicroRNAs are a new class of small non-protein-coding RNAs that sometimes function as tumor suppressors or oncogenes. Aberrant expression and structural alteration of microRNAs have been reported to be involved in tumorigenesis and cancer development. Recently, rs531564/pri-miR-124-1, rs4938723/pri-miR-34b/c, rs7372209/pri-miR-26a-1, rs895819/pre-miR-27a, and rs11134527/pri-miR-218 w...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید