The purpose of this study was to investigate the efficacy of phototherapy with a newly-developed 1450-nm diode laser in patients with mild to moderate acne. An open study was performed in acne patients who were treated up to five times with a two week interval. Acne lesions were reduced by 63%. Only one patient discontinued treatment due to vesicle formation as an adverse effect. Phototherapy u...

background: acne vulgaris is a chronic inflammatory disease of the pilosebaceous follicles and one of the most common skin diseases.the peeling method has been recently found to be effective for acne treatment. this study aimed to compare the efficacy of pyruvic acid 50% and salicylic acid 30% peeling in the treatment of mild to moderate acne. materials and methods: in a prospective single?blin...

BACKGROUND Acne is considered a cosmetic nuisance in Malaysia since no insurance coverage is provided for its treatment. Its psychological impact is unknown. OBJECTIVE The aim of this study is to determine the impact of acne on quality of life and its relationship with severity. METHODS A cross-sectional study using the Cardiff acne disability index (CADI) and Global Acne Grading System for...

Topical retinoids, benzoyl peroxide, azelaic acid, and topical and oral antibiotics remain the milestone of treatment for mild to moderate acne vulgaris. Oral isotretinoin is useful for the treatment of severe nodular acne, treatment-resistant acne, and acne with a risk of physical or psychological scarring. Hormonal treatment in female acne is useful in resistant or late-onset acne. With incre...

There is compelling evidence that oral contraceptives (OCs) are effective in the management of mild-moderate acne vulgaris, as well as cumulative evidence that elevated levels of androgens in acne patients, relative to appropriate controls, are an underlying pathophysiological factor in acne. All low dose OCs reduce serum free testosterone (T) to a similar extent, which is contrary to the tradi...

BACKGROUND Photodynamic therapy (PDT) has been shown to be an effective alternative for acne. However, there is little information comparing the efficacy of red light alone and methyl aminolaevulinate (MAL)-PDT. AIMS To compare the efficacy and tolerability of red light alone and MAL-PDT in patients with mild to moderate facial acne. METHODS Thirty six patients with mild to moderate acne we...

Background: At-home phototherapy devices for the treatment of acne have emerged as an appealing treatment option and as an effective adjunct treatment to existing modalities. The principal goal of the study was to determine the changes in the number of inflammatory lesions in acne patients. Methods: Patients received instruction for daily at-home use of Silk’n Blue device for 12 weeks. Follow-u...

One of the common chronic inflammatory skin diseases is Acne Vulgaris that affects up to 80% of a teen-age population. The progress of acne lesions is due to colonization of Propionibacterium acnes (P .acnes) in hair follicles. Treatment of acne includes topical or systemic therapy or combination therapy, with a tendency to perform topical therapy in mild to moderate acne. Nanoemulsions, small ...

BACKGROUND Twenty percent azelaic acid gel is recommended as a topical treatment for acne due to its favorable profile. AIM Our objective in this study was to evaluate the efficacy of 20% azelaic acid gel in the treatment of mild to moderate acne vulgaris. METHODS This was a double blind, randomized clinical trial. Sixty patients with mild to moderate acne vulgaris were selected randomly to...

Acne represents a significant challenge to dermatologists because of its prevalence, complexity and range of clinical expression. It is the single most common skin disease affecting 85% of teenage boys and 80% of teenage girls and can continue throughout adulthood. Treatment of acne with topical and systemic allopathic medicines results in mild to severe side effects. Hence, herbs and herbal pr...