The process of cell division represents an extraordinary target to develop antitumor therapies. Indeed, a large number of clinically relevant anticancer drugs, such as taxanes and vinca alkaloids, target mitosis by stimulating or inhibiting microtubule (MT) polymerization. During the past decades anti-tubulin drugs have proven very effective against a wide range of tumors. However, collateral e...

Articles you may be interested in Vertically integrated metal-clad/silicon dioxide-shell microtube arrays for high-spatial-resolution light stimuli in saline Appl. On-chip intra-and inter-layer grating couplers for three-dimensional integration of silicon photonics Appl. Monolithically integrated low-loss silicon photonic wires and three-dimensional tapered couplers fabricated by self-profile t...

Calibration of flow devices is important in several areas pharmaceutical, chemistry and microfluidic applications where dosage process liquids or accurate measurement rate important. The process-oriented liquid itself might influence the performance a device simultaneous determination dynamic viscosity under conditions provide valuable information for parameters. To offer calibration at corresp...

Neisseria species are identified in most diagnostic microbiology laboratories by using carbohydrate degradation methods. Conventional methods require 24 to 48 h of incubation for completion of the test (15). A number of rapid methods which employ various agar bases, growth factors, sugar concentrations, agar concentrations, inoculum sizes, filter paper disks, radiometry, gas chromatography, spe...

[This corrects the article on p. 902 in vol. 2, PMID: 26697517.].

in this paper, direct numerical simulation of two-phase incompressible gas-liquid flow for simulation of bubble motion in a microtube is presented. microtube radius is 10 µm. the interface is tracked using volume of fluid (vof) method with continuous surface force (csf) model. the flow is solved using a finite volume scheme, based on piso algorithm. numerical simulation is performed on a axisym...