Microscopic colitis (MC) is emerging as an increasingly common cause of chronic and debilitating watery diarrhea in the adult population. The term microscopic colitis was first coined by Park et al in 1980 as an entity causing persistent watery diarrhea [1]. It was initially characterized by chronic watery diarrhea and normal endoscopic findings with abnormal histopathology on biopsy [2]. Micro...

Crocin, as a carotenoid compound of saffron, exerts a potent antioxidant property. Mesalazine is frequently used in the treatment of ulcerative colitis. This study investigated the effects of separated and combination treatments with crocin and mesalazine in a rat model of ulcerative colitis. Ulcerative colitis was induced by intra-colonic administration of acetic acid (4.00%, 1.00 mL) at 8 cm ...

mainly includes two diseases: collagenous colitis and lymphocytic colitis. The diagnosis relies on specific microscopic changes seen in colonic mucosal biopsies. Collagenous colitis was first described in 1976 by Lindström and the typical patient is a middle-aged or elderly woman, with the female-to-male ratio approximately 7: 1. Dear Sir, An 80-year-old Japanese woman was admitted to our hospi...

BACKGROUND There is increasing evidence for the role of microscopic inflammation in patients with IBS. We aimed to examine the prevalence of microscopic colitis and inflammation in Malaysian IBS patients with diarrhoea (IBS-D). METHODS Consecutive patients who met the Rome III criteria for IBS-D and asymptomatic controls were prospectively recruited. Colonoscopy was performed in all study sub...

BACKGROUND Irritable bowel syndrome (IBS) is a chronic functional bowel disorder. The frequency of microscopic colitis and focal active colitis in the colonic mucosa has been investigated in IBS patients. METHODS Between June 2007 and September 2010, 378 patients (between 16 and 84 years) were recruited prospectively. Of these 378 patients, 226 patients were diagnosed with IBS using the Rome ...

The diagnosis of both CC and LC is based on a compatible clinical picture and well-established objective histological criteria. The motivation degree of the involved physicians is essential in the diagnosis of microscopic colitis. The gastroenterologist should refer every patient with chronic watery diarrhea to perform a colonoscopy in spite of the benign course of the disease and the absence o...

colitis is an inflammatory disease of the intestine with unknown etiology involving multiple immune, genetic and environmental factors. we were interested to examine the effect of total extract from pycnocycla spinosa boiss. on the treatment of experimental colitis. mediators involved in colonic inflammation are prostaglandins, interleukins, leukotriene as well as an increase in myeloperoxidase...