نتایج جستجو برای: micro vessels

تعداد نتایج: 172633  

Background and Aim: Sulforaphane is a type of isothiocyanate with anticancer effects. In the present study, the effect of sulforaphane in angiogenesis in chicks' chorioallantoic membrane was investigated. Materials and Methods: In this experimental study, a total of 56 fertilized eggs were divided into 7 groups of eight with three replications: control, control-Experimental and five treatment...

2016
Daniel J. Smith Gabriel A. Brat Scott H. Medina Dedi Tong Yong Huang Johanna Grahammer Georg J. Furtmüller Byoung Chol Oh Katelyn J. Nagy-Smith Piotr Walczak Gerald Brandacher Joel P. Schneider.

Many surgeries are complicated by the need to anastomose, or reconnect, micrometre-scale vessels. Although suturing remains the gold standard for anastomosing vessels, it is difficult to place sutures correctly through collapsed lumen, making the procedure prone to failure. Here, we report a multiphase transitioning peptide hydrogel that can be injected into the lumen of vessels to facilitate s...

Journal: :Blood 2000
H Kubo T Fujiwara L Jussila H Hashi M Ogawa K Shimizu M Awane Y Sakai A Takabayashi K Alitalo Y Yamaoka S I Nishikawa

Vascular endothelial growth factor (VEGF) plays a major role in tumor angiogenesis. VEGF-C, however, is thought to stimulate the growth of lymphatic vessels because an expression of its specific receptor, VEGF receptor-3 (VEGFR-3), was demonstrated to be restricted to lymphatic vessels. Here we demonstrate that the inactivation of VEGFR-3 by a novel blocking monoclonal antibody (mAb) suppresses...

Journal: :Clinical hemorheology and microcirculation 2010
B Hiebl R Fuhrmann F Jung K Kratz A Lendlein R P Franke

The degradation behavior and the effect on angiogenesis of multiblock copolymers based on poly(p-dioxanone)- and poly(epsilon-caprolactone)-segments (PDC) were studied in vivo. PDC is a multifunctional biomaterial combining degradability and shape-memory capabilities. The "in vivo" degradation of PDC is characterized by a fragmentation occurring at the material tissue interface. This observatio...

Journal: :Thrombosis and haemostasis 2013
Josef Ehling Twan Lammers Fabian Kiessling

Noninvasive imaging plays an emerging role in preclinical and clinical cancer research and has high potential to improve clinical translation of new drugs. This article summarises and discusses tools and methods to image tumour angiogenesis and monitor anti-angiogenic therapy effects. In this context, micro-computed tomography (µCT) is recommended to visualise and quantify the micro-architectur...

2001
Shu-Mei Wu Yio-Wha Shau Bor-Shyh Lin Fok-Ching Chong

We studied the effect of mechanical pumping on the response of peripheral arteries by focusing on the pulse wave velocity (PWV) in large arterial conduit and micro-vessels. The pressure waveforms were measured simultaneously at the brachial artery (BA), radial artery (RA) and finger. Impulse pumping was operated by alternatively adding 80mmHg pressure to the arm of normal subjects (N=10) in 3 s...

Journal: :American journal of physiology. Heart and circulatory physiology 2011
Monique Y Rennie Jacqui Detmar Kathie J Whiteley Jian Yang Andrea Jurisicova S Lee Adamson John G Sled

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants and the main toxicants found in cigarettes. Women are often exposed to PAHs before pregnancy, typically via prepregnancy smoking. To determine how prepregnancy exposure affects the fetoplacental vasculature of the placenta, we exposed female mice to PAHs before conception, perfused the fetoplacental arterial trees w...

2017
Pradeep Kumar

Diabetes strikes when the pancreas stops to produce sufficient insulin, gradually disturbing the retina of the human eye, leading to diabetic retinopathy. The blood vessels in the retina become changed and have abnormality. Exudates are concealed, micro-aneurysms and haemorrhages occur in the retina of eye, which intern leads to blindness. The presence of these structures signifies the harshnes...

2014
Laura Nebuloni Gisela A. Kuhn Johannes Vogel Ralph Müller

The vasculature of body tissues is continuously subject to remodeling processes originating at the micro-vascular level. The formation of new blood vessels (angiogenesis) is essential for a number of physiological and pathophysiological processes such as tissue regeneration, tumor development and the integration of artificial tissues. There are currently no time-lapsed in vivo imaging technique...

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