abstract background: autosomal dominant polycystic kidney disease (adpkd) is an inherited disorder with genetic heterogeneity. up to three loci are involved in this disease, pkdi on chromosome 16p13.3, pkd2 on 4q21, and a third locus of unknown location. methods: here we report the first molecular genetic study of adpkd and the existence oflocus heterogeneity for adpkd in the iranian population...

background: hearing loss (hl) is the most frequent sensory birth defect in humans. autosomal recessive non-syn­dromic hl (arnshl) is the most common type of hereditary hl. it is extremely heterogeneous and over 70 loci (known as dfnb) have been identified. this study was launched to determine the relative contribution of more frequent loci in a cohort of arnshl families. methods: thirty-seven i...

designing breeding programs for winter rapeseed (brassica napus l.) cultivars with improved seed and oil yields requires information about the genetic variability of traits. in this study, 28 winter rapeseed cultivars were evaluated for genetic variation and relationships between 11 agro-morphological characters during 2010 and 2011. cultivars and cultivar × year interaction showed significant ...

this study was conducted in order to investigate genetic diversity and population structure of pike-perch in the northern part of iran. for this purpose, 207 adult pike-perches from four regions of the caspian sea watershed (talesh coasts, anzali wetland, chaboksar coasts and aras dam) were collected. dna was extracted and by using 15 pairs of microsatellite primers, polymerase chain reaction (...

combining ability effects were estimated for different agronomic characters in line × tester crossing program comprising 21 hybrids produced by crossing 7 lines and 3 testers. parents and hybrids differed significantly for general combining ability (gca) and specific combining ability (sca) effects, respectively. the variance due to gca and sca showed that gene action was predominantly additive...

1 Mixed traffic, characterized by diverse vehicles, changing composition, lack of lane discipline, etc. is best modeled 2 by micro simulation. However, the majority of the leading micro simulation packages and their calibration 3 methodologies have been developed considering less complex homogeneous traffic. Hence, a methodology for 4 calibrating a micro simulation model for mixed traffic is pr...

Whole-cell bio-chips for functional sensing integrate living cells on miniaturized platforms made by micro-system-technologies (MST). The cells are integrated, deposited or immersed in a media which is in contact with the chip. The cells behavior is monitored via electrical, electrochemical or optical methods. In this paper we describe such whole-cell biochips where the signal is generated due ...

The paper gives an analytical approximation to the viscous damping coefficient due to the motion of a gas between a pair of closely spaced fluctuating plates in which one of the plates contains a regular system of circular holes. These types of structures are important parts of many microelectromechanical devices realized in MEMS technology as microphones, microaccelerometers, resonators, etc.T...

performance optimization of a single-effect lithium bromide water absorption refrigerationsystem is the subject of this paper. first, the thermodynamic model of the system wasderived based on thefirst and second law analysis of an absorption refrigeration cycle with libr-water as the working fluid pair.then, the effects of different design parameters such as the generator inlet hot water temper...

Leaf senescence constitutes the last stage of leaf development in plants and proceeds through a highly regulated program in order to redistribution of micro- and macro-nutrients from the senescing leaves to the developing/growing plant organs. Initiation and progression of leaf senescence is accompanied by massive sequential alterations at various levels of leaf biology including leaf morpholog...