نتایج جستجو برای: michigan cancer foundation7 cells
تعداد نتایج: 2102575 فیلتر نتایج به سال:
runx3, a member of runt-related transcription factor (runx) proteins with tumor suppressor effect, is a tissue–restricted and cancer related transcription factor that regulate cell proliferation and growth, as well as differentiation. in the present study, exogenous run3 was transiently expressed in ags (human gastric adenocarcinoma), with undetectable runx3 protein and in a549 (human lung carc...
circulating tumor cells (ctcs) recognition and characterization in the peripheral blood of patients with breast cancer have proven practical and predictive value in different studies. however, the clinical significance of ctcs enumeration and molecular characterization in thepersonalization of breast cancer diagnosis and treatment remains under the debate. a literature search in pubmed, web of ...
background: the use of dendritic cells (dcs) as a cellular adjuvant provides a promis-ing approach in immunotherapy of cancer. it has been demonstrated that listeria mono-cytogenes activated dcs pulsed ex vivo with tumor antigens trigger a systemic th1-biased specific immune response and a single dose of this vaccine will cause a consider-able anti tumor immunity. objective: the present study w...
Affiliations 1. Michigan Center for Translational Pathology, University of Michigan Medical School 2. Department of Pathology, University of Michigan Medical School 3. Department of Dermatology, University of Michigan Medical School 4. Department of Biomedical Science, Bharathidasan University, Tiruchirappalli, India 5. Department of Urology, Henry Ford Health System, Detroit, MI 6. Howard Hugh...
objective: immunotoxins (its) have been developed for the treatment of cancer, and comprise of antibodies linked to toxins. also vascular endothelial growth factor (vegf) plays a key role in tumor angiogenesis, and the blockade of vegf receptor-2 (vegfr2) inhibits angiogenesis and tumor growth. the aim of this study was to produce anti-vegfr2/rpe (pseudomonas exotoxin) 38 it to test its cytotox...
Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA. Diabetes Center, University of California, San Francisco, 94143 California, USA. Department of Pathology, Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA. Medical Scientist Training Program, University of Michigan Medical School, Ann Ar...
conclusions due to the significant reduction in the mean inactivation dose of colon cancer cells in the presence of gold nanoparticles, it seems that gnps are suitable options to achieve a new approach in order to improve radiotherapy efficiency without increasing the prescribed radiation dose. results cell survival in the presence of gnps was more than 90% and the maximum uptake of gnps was ob...
Background and purpose: Angiogenesis provides proper nutrition and helps to the development and spread of cancer cells. Cancer stem cells are a rare population of tumor cells responsible for initiation, spreading and growth of cancer. Angiogenesis occurs more in cancer stem cells compared with other cancer cells. Ibuprofen, as a member of nonsteroidal anti-inflammatory drugs (NSAIDs) group is u...
Introduction Although some circRNAs have been found to regulate the progression of malignancies, their functions and coupled molecular mechanisms are still unclear. In our study, we sought to assess the underlying molecular mechanisms of circRNAs in breast cancer and therefore explored the differentially expressed circRNAs and co-expression networks, followed by in vitro experiments. Material...
in recent years many researchers have been focused on interaction of small molecules with dna. dna is generally the primary intracellular of anticancer drugs, so the interaction between small molecules and dna can cause dna damage in cancer cells, blocking the division of cancer cells and resulting in cell death. the flavonoids are a large group of polyphenolic natural products that are widely ...
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