نتایج جستجو برای: mice bax and bcl 2 genes real time pcr brain
تعداد نتایج: 17613575 فیلتر نتایج به سال:
Introduction: Breast cancer is one of the most prevalent malignancies among women. Patients whose suffering from this condition, as a result of the use of conventional therapies often have a poor response to treatment and the relapse among them is frequent. In this study, the effects of staphylococcal enterotoxin type B on BAK، FAS، BAX، TNF-a، BCL-2 و Survivin genes expression in human breast ...
Objective(s): Being secreted by the pineal gland, melatonin induces cell proliferation in normal cells and induced apoptosis in cancer cells. The purpose of this study was to investigate effects of melatonin on main components and the expression of apoptotic genes in vitrified-thawed testicular germ cells of 6- day–old mice. Materials and Methods: Testes of neonate Balb/c mice were vitrifie...
objective(s): being secreted by the pineal gland, melatonin induces cell proliferation in normal cells and induced apoptosis in cancer cells. the purpose of this study was to investigate effects of melatonin on main components and the expression of apoptotic genes in vitrified-thawed testicular germ cells of 6- day–old mice. materials and methods: testes of neonate balb/c mice were vitrified-...
Zerumbone (ZER), a natural compound has been extracted from Zingiber zerumbet with known pharmacological activities. The aim was to determine the anti-human Burkitt’s lymphoma (Raji) cell effect of ZER. 3-(4,5-dimethylthiazol-2-yl)-2,5,-diphenyltetrazolium bromide (MTT) assay used cytotoxic while Annexin-V-fluorescein isothiocyanate/propidium iodide-PI flow cytometric assays apoptotic ZER on hu...
Background: Vitrification of oocytes is a fast-freezing technique, which may affect the quality of the human oocyte, and consequently affects the embryo development, pregnancy and birth. The aim of the current study was to investigate the consequence of in-vitro vitrification on maturation status of immature human oocytes, additionally, expression levels of stress, and apoptosis related genes. ...
objective: to evaluate the mrna expression ratio of bcl-2/bax both in normal and tumoral bladder tissues of patients with transitional cell carcinoma (tcc) of bladder and investigate potential correlation between this expression ratio and clinical outcome. materials and methods: in this experimental study, we used real time-pcr to investigate the expression of bcl-2 and bax both in normal and t...
Introduction: Some factors such as exercise training and pharmacological interventions can slow tumor growth. To determine the underlying mechanisms, we investigated the effect of six weeks of interval exercise training along with ingestion on Bcl-2 and LC3 genes expression in the tumor tissue of breast tumor–bearing mice. Methods: Twelve female BALB/c mice were injected with cancer cell line a...
Background and Objectives: Researches have shown that progesterone influences the viability of breast cancer cells. The purpose of this study was to investigate the effect of progesterone on the viability of MCF-7 cell line and evaluation of Expression level of P53, Bax, and Bcl-2 Genes. Methods: In this laboratory-experimental study, MCF-7 cells were purchased from Pasture institute and div...
Background: In this study, we evaluated the incidence of apoptosis at the ultrastructural levels and expression of some apoptosis-related genes in vitrified human ovarian tissue just after warming. Methods: Human ovarian tissue biopsies from 23 women after caesarean section were transported to the laboratory within 2 hours, and then they were cut into small pieces. Some pieces were vitrified an...
Background: The Peucedanum species have many pharmacological effects due to the presence of coumarins, flavonoids, phenolic compounds, and essential fatty acids in these species. In this study, for the first time, the anticancer activity of Peucedanum chenur methanolic extract via the induction of apoptosis and inhibition of invasion in HCT-116 human colon cancer cells was investigated. Methods...
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