The applicability of MIB-1, a monoclonal antibody directed against the Ki-67 antigen, was studied in the PC-82 and LNCaP prostatic tumor models at various levels of proliferative activity. Statistically significant correlations were found in LNCaP cultures between Ki-67 and MIB-1 scores (r = 0.84, P < 0.001), and in PC-82 tumors between MIB-1 scores and paraffin tissue Ki-67 (pKi-67) (r = 0.90,...

This memo defines a portion of the Management Information Base (MIB) for devices implementing Network Address Translator (NAT) function. This MIB module may be used for configuration as well as monitoring of a device capable of NAT function. Rohit, et al. Standards Track [Page 1] RFC 4008 NAT MIB March 2005

1. Status of this Memo This memo defines the second version of the Management Information Base (MIB-II) for use with network management protocols in TCP/IP-based internets. In particular, together with its companion memos which describe the structure of management information (RFC 1155) along with the network management protocol (RFC 1157) for TCP/IP-based internets, these documents provide a s...

AIMS To determine cell proliferation in infiltrating breast carcinomas. METHODS Using the MIB-1 monoclonal antibody, the proliferation index was measured in paraffin wax sections of 871 breast cancers. The MIB-1 proliferation index was compared with other markers of disease progression: size, lymph node status, histotype, oestrogen and progesterone receptor status, expression of p53 and Neu, ...

The pathogenesis of endocervical glandular lesions are not clearly understood. The aims of this study are to evaluate the etiologic role of human papillomavirus (HPV) 16/18 and the relationship of HPV 16/18, p53 and MIB-1 expressions in endocervical glandular dysplasia (EGD), adenocarcinoma in situ (AIS) and adenocarcinoma. The materials included 14 endocervical adenocarcinoma and 5 AIS and 18 ...

Background Previous studies have investigated the prognostic significance of Ki-67/MIB-1 expression in renal cell carcinoma (RCC), however, the reports are controversial and inconsistent. This study aimed to investigate Ki-67/MIB-1 expression in RCC and its correlation with prognosis and clinicopathological features. Methods We searched relevant studies that reported associations between Ki-6...

In motion-induced blindness (MIB), persistent static targets intermittently disappear when presented near moving elements [1, 2]. There is currently no consensus regarding the cause or causes of MIB [3-7]. Here, we link the phenomenon to a mechanism that is integral for normal human vision, motion streak suppression [8]. The human visual system integrates information over time [9], resulting in...

The usual way to describe the semantics of MIB objects is just to give an informal English text explaining each object’s behavior. Informal descriptions are vague and incomplete. They are open to misinterpretation and may lead to inconsistent implementations. In this work we propose the use of Action Semantics as a simple and powerful tool for the formal description of the behavior of MIB objec...

BACKGROUND A significant relationship has been reported in which Ki-67/MIB-1 expression is correlated with survival in cervical cancer patients. However, the prognostic value of Ki-67/MIB-1 in cervical cancer is still not well understood. MATERIAL AND METHOD A meta-analysis was carried out to explore the prognostic value of Ki-67/MIB-1 on overall survival (OS) and/or disease-free survival (DF...

The biological aggressiveness of lymph node-positive prostate cancer is closely linked to cancer volume in nodal metastases. We evaluated MIB-1 (Ki-67) labeling index and bcl-2 expression in primary cancer and matched nodal metastases from 138 node-positive patients treated with radical prostatectomy and bilateral pelvic lymphadenectomy between 1987 and 1992 at the Mayo Clinic. One hundred twen...