Motion-induced blindness (MIB) is one of the most enigmatic perceptual disappearance phenomena. Here we suggest that MIB may be caused by the combined effects of two distinct adaptation processes: one shared with two other non-MIB configurations and entailing a response-gain reduction, and a second, MIB-specific transient-to-sustained incremental inhibition causing a contrast-gain reduction. Re...

Notch signaling pathway defines an evolutionarily conserved mechanism in cell-fate determination in a broad spectrum of developmental processes through local cell interactions. mind bomb (mib) encodes an E3 ubiquitin ligase that is involved in Notch activation through Delta ubiquitylation and internalization. To further dissect the function of Mib, two yeast two-hybrid screens for zebrafish Mib...

This study aimed to determine the regulation of the de novo myo-inositol biosynthetic (MIB) pathway in Mozambique tilapia (Oreochromis mossambicus) brain following acute (25 ppt) and chronic (30, 60 and 90 ppt) salinity acclimations. The MIB pathway plays an important role in accumulating the compatible osmolyte, myo-inositol, in cells in response to hyperosmotic challenge and consists of two e...

It has been suggested that subjective disappearance of visual stimuli results from a spontaneous reduction of microsaccade rate causing image stabilization, enhanced adaptation, and a consequent fading. In motion-induced blindness (MIB), salient visual targets disappear intermittently when surrounded by a moving pattern. We investigated whether changes in microsaccade rate can account for MIB. ...

Commonly detected in surface waters worldwide, odorous compounds such as geosmin (GSM) and 2-methylisoborneol (MIB) pose important issues drinking water aquaculture industries. Impaired are frequently plagued by severe Cyanobacterial blooms seasonal occurrences of Actinobacteria due to increased anthropogenic stressors well climate change that negatively impact the quality resources globally. H...

Abstract It is common practice to use the well-known concept of minimal detectable bias (MDB) assess performance statistical testing procedures. However, such procedures are usually applied a null and set multiple alternative hypotheses with aim selecting most likely one. Therefore, in DIA method for detection, identification adaptation model misspecifications, rejection hypothesis followed by ...

Various protocols have been proposed and developed to manage communication networks efficiently, which are becoming increasingly complex. Of those protocols, SNMP has been popular because it is easy to implement and widely available. However, it has problems in terms of scalability and security. CMIP is a good alternative to SNMP, and OSI MIB provides diverse features to model complex communica...

This study was conducted to obtain the basic data of two common odorants-geosmin and 2-methylisoborneol (GSM and 2-MIB)-in environmental water. More specifically, the headspace solid-phase microextraction coupled to gas chromatography mass spectrometry (HS-SPME/GC-MS) was applied to determine the levels of GSM and 2-MIB in water samples, and the samples were collected depending on water sources...

This memo defines a portion of the Management Information Base (MIB), the Mobile-IPv6 MIB, for use with network management protocols in the Internet community. In particular, the Mobile-IPv6 MIB will be used to monitor and control the mobile node, home agent, and correspondent node functions of a Mobile IPv6 (MIPv6) entity.

Background Mibefradil (MIB), previously approved for treatment of hypertension, is a selective T-type calcium channel blocker with preclinical activity in high-grade gliomas (HGGs). To exploit its presumed mechanism of impacting cell cycle activity (G1 arrest), we designed a phase I study to determine safety and the maximum tolerated dose (MTD) of MIB when given sequentially with temozolomide (...