What if {a tourist, a train addict, Dr. Sheldon Cooper, somebody who likes to waste time} wants to visit all metro lines or carriages in a given network in a minimum number of steps? We study this problem with an application to the Parisian metro network and propose optimal solutions thanks to mathematical programming tools. Quite surprisingly, it appears that you can visit all 16 Parisian metr...

In this paper we investigate the problem of drawing metro maps which is defined as follows. Given a planar graph G of maximum degree 8 with its embedding and vertex locations (e.g. the physical location of the tracks and stations of a metro system) and a set L of paths or cycles in G (e.g. metro lines), draw G and L nicely. We first specify the niceness of a drawing by listing a number of hard ...

The metro door system is one of the high failure rate subsystems of metro trains. The Failure Mode, Effects and Criticality Analysis (FMECA) method is applied to analyze the reliability of metro door system in this paper. Firstly, failure components of the door are statistically analyzed, and the major failure components are determined. Secondly, failures are classified according to their impac...

The function of a metro station area is vital for city planners to consider when establishing a context-aware Transit-Oriented Development policy around the station area. However, the functions of metro station areas are hard to infer using the static land use distribution and other traditional survey datasets. In this paper, we propose a method to infer the functions occurring around the metro...

Most transit networks are designed empirically. For bus networks this process 1s often satisfactory because bus routes and networks are very dependent on local conditions, and they can be easily modified, allowing easy corrections of problems which line design may cause in operations. However, with transit systems which have extensive infrastructure, most typically metro lines and networks, cor...

OBJECTIVES To compare the pharmacodynamics and tolerability of the new goserelin acetate 10.8-mg depot with the 3.6-mg depot in patients with advanced prostate cancer during the first 3 months of therapy. METHODS One hundred sixty patients were randomized in two comparative studies to receive either the 10.8-mg goserelin acetate depot every 12 weeks or the 3.6-mg goserelin acetate depot every...

Long-acting depot antipsychotics were developed specifically to promote treatment adherence (compliance) and they are a valuable option for patients requiring maintenance medication for schizophrenia. Depot use has fallen in recent years, perhaps owing to the introduction of oral atypical antipsychotics. Psychiatrist and patient acceptance of depot medication is variable. The depot formulation ...

long protocol of gonadotropin-releasing hormone-analougue (gnrh-a) can result in the formation of ovarian cyst by the transient initial stimulatory effect which increases the levels of both follicle-stimulating hormone (fsh) and luteinizing hormone (lh). these cysts require surgical drainage or result in poor ovarian response. ovarian cyst formation can be prevented by taking oral contraceptive...