1. Colloidal mercuric sulfide or thorium dioxide injected intraperitoneally passes into the cytoplasm of the mesothelium of the mesentery and of the diaphragm as early as 15 to 30 minutes after the injection. 2. Between 15 minutes and 12(1/2) hours the number of particles within the mesothelial cells increases as the time between injection and termination of the experiment is lengthened. 3. The...

We have previously shown that CD44 partly mediates ovarian cancer cell attachment to peritoneal mesothelium through recognition of mesothelial-associated hyaluronate. CD44 is a major receptor for hyaluronate and exists as a standard 90-180-kDa form (CD44H), as well as several higher molecular mass variant forms produced by alternative splicing. To determine whether functional differences exist ...

toneal mesothelium predominantly express the 90-kDa CD44H mol ecule, whereas ovarian cancer lines that bind poorly to mesothelium express either absent or relatively low levels of CD44H (2, 3). Furthermore, transfection of weakly binding ovarian cancer cells with CD44H cDNA is capable of restoring their ability to bind to mesothe hum in vitro (3). Finally, treatment of mesothelial monolayers wi...

The pleural membrane consisting of pleural mesothelial cells and its underlying connective tissue layers play a critical role in immunological responses in both local and systemic diseases. The pleura, because of its intimate proximity to the lung, is positioned to respond to inflammatory changes in the lung parenchyma. Importantly, several systemic diseases have a predilection for expression o...

Objective: Parietal and the visceral layers of mesothelium are separated by a thin layer lubricating fluid made up single flat cells. The three body cavities pleura, peritoneum, pericardium lined mesothelium. collection inside these is called an effusion may be due to variety inflammatory, infective, neoplastic causes often reactive mesothelial cells hyperplasia that sometimes very hard differe...