نتایج جستجو برای: mesenchymal transition

تعداد نتایج: 307477  

Journal: :Journal of advances in medical and biomedical research 2022

Mesenchymal Stem Cells Trigger Epithelial to Transition in the HT-29 Colorectal Cancer Cell Line

2009
Astrid M Doerner Bruce L Zuraw

BACKGROUND Chronic persistent asthma is characterized by ongoing airway inflammation and airway remodeling. The processes leading to airway remodeling are poorly understood, and there is increasing evidence that even aggressive anti-inflammatory therapy does not completely prevent this process. We sought to investigate whether TGFbeta1 stimulates bronchial epithelial cells to undergo transition...

Journal: :Molecular Biology of the Cell 2006

Journal: :Frontiers in Cell and Developmental Biology 2020

Journal: :Indo Global Journal of Pharmaceutical Sciences 2014

2016
Avijit Pramanik Aruna Vangara Bhanu Priya Viraka Nellore Sudarson Sekhar Sinha Suhash Reddy Chavva Stacy Jones Paresh Chandra Ray

Circulating tumor cells (CTC) are highly heterogeneous in nature due to epithelial-mesenchymal transition (EMT), which is the major obstacle for CTC analysis via "liquid biopsy". This article reports the development of a new class of multifunctional fluorescent-magnetic multicolor nanoprobes for targeted capturing and accurate identification of heterogeneous CTC. A facile design approach for th...

2014
Y. A. Shelygin N. I. Pospekhova V. P. Shubin V. N. Kashnikov S. A. Frolov O. I. Sushkov S. I. Achkasov A. S. Tsukanov

Colorectal cancer is highly metastatic even when the tumors are small. To disseminate, cells use a complex and multistage process known as the epithelial-mesenchymal transition, in which epithelial phenotype is transformed into mesenchymal phenotype. The objective of this study is to describe the epithelial-mesenchymal transition in terms of gene expression profile and somatic alterations in sa...

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