نتایج جستجو برای: mesenchymal stromal cell

تعداد نتایج: 1733547  

Journal: :Advanced Healthcare Materials 2022

On-Chip Technologies In article number 2101995, using 3D encapsulation and microfluidics, Andrés J. García co-workers engineer a high-throughput on-chip human mesenchymal stromal cell (MSC) potency assay with improved functional prediction compared to traditional 2D assays. Further results demonstrate in vivo secretory recapitulation of MSCs cultures.

Journal: :Haematologica 2010
Selim Kuçi Zyrafete Kuçi Hermann Kreyenberg Erika Deak Kathrin Pütsch Sabine Huenecke Chandrasekhar Amara Stefanie Koller Eva Rettinger Manuel Grez Ulrike Koehl Hatixhe Latifi-Pupovci Reinhard Henschler Torsten Tonn Dorothee von Laer Thomas Klingebiel Peter Bader

UNLABELLED Background In vitro proliferative and differentiation potential of mesenchymal stromal cells generated from CD271(+) bone marrow mononuclear cells (CD271-mesenchymal stromal cells) has been demonstrated in several earlier and recent reports. In the present study we focused, in addition to proliferative and differentiation potential, on in vitro and in vivo immunosuppressive and lymph...

Journal: :Macromolecular Bioscience 2022

Back Cover: In article number 2200071, Kenneth Dalgarno and co-workers describe the reactive jet impingement bioprinting system as an effective strategy to deliver high cell concentrations directly onto metal surfaces with various topographies. Mesenchymal stromal cells are bioprinted in soft hydrogel matrices that provide extracellular matrix-like environment. The cell-laden hydrogels integrat...

آی, جعفر , امیدفر, کبری , صدرالدینی, اسماعیل , عینی, لیلا , لاریجانی , باقر, مجیدزاده, کیوان , نقاش, نگار ,

Background: Mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells, are considered as an important source of adult stem cells in tissue engineering and cell therapy. They are present in various tissues such as, endometrium as the supportive cells. According to anatomical position of endometrial mesenchymal stem cells that put them in neighborhood of the fetus, they m...

2015
Giovanna Calabrese Raffaella Giuffrida Debora Lo Furno Nunziatina Laura Parrinello Stefano Forte Rosario Gulino Cristina Colarossi Luciana Rita Schinocca Rosario Giuffrida Venera Cardile Lorenzo Memeo Wenbin Deng

The Low-Affinity Nerve Growth Factor Receptor (LNGFR), also known as CD271, is a member of the tumor necrosis factor receptor superfamily. The CD271 cell surface marker defines a subset of multipotential mesenchymal stromal cells and may be used to isolate and enrich cells derived from bone marrow aspirate. In this study, we compare the proliferative and differentiation potentials of CD271+ and...

2016
Luca Genovese Andrea Brendolan

Secondary lymphoid organs (SLOs) are sites that facilitate cell-cell interactions required for generating adaptive immune responses. Nonhematopoietic mesenchymal stromal cells have been shown to play a critical role in SLO function, organization, and tissue homeostasis. The stromal microenvironment undergoes profound remodeling to support immune responses. However, chronic inflammatory conditio...

Journal: :Haematologica 2015
Friso G J Calkoen Carly Vervat Else Eising Lisanne S Vijfhuizen Peter-Bram A C 't Hoen Marry M van den Heuvel-Eibrink R Maarten Egeler Maarten J D van Tol Lynne M Ball

An aberrant interaction between hematopoietic stem cells and mesenchymal stromal cells has been linked to disease and shown to contribute to the pathophysiology of hematologic malignancies in murine models. Juvenile myelomonocytic leukemia is an aggressive malignant disease affecting young infants. Here we investigated the impact of juvenile myelomonocytic leukemia on mesenchymal stromal cells....

Journal: :Plastic and reconstructive surgery 2015
Pranitha Kamat Riccardo Schweizer Philip Kaenel Souzan Salemi Maurizio Calcagni Pietro Giovanoli Vijay S Gorantla Daniel Eberli Anne-Catherine Andres Jan A Plock

BACKGROUND Stem cell-enriched fat grafting has been proposed as a potential therapy for reconstructive, restorative, or enhancement-related procedures of the breast. Its role in postoncologic breast reconstruction is still emerging, with concerns about safety. The authors investigated the dose-dependent interaction between human adipose-derived mesenchymal stromal cells (AD-MSCs) and human brea...

ژورنال: Anatomical Sciences Journal 2006
Jafar Nezhad, Seyed Mahdi, Moghadam Matin, Maryam, Moula, Seyed Javad,

Purpose: The aim is to downregulate the expression level of NS as an important factor in sustaining stem cells and certain types of cancer cells self-renewal ability in bone marrow derived mesenchymal stem cells by RNAi strategy and investigate the effects of absence of NS in these cells. Materials and Methods: Double strand NS-specific and control siRNA oligos were designed and transfected in...

2013
Thibaud André Nathalie Meuleman Basile Stamatopoulos Cécile De Bruyn Karlien Pieters Dominique Bron Laurence Lagneaux

BACKGROUND In multiple myeloma, bone marrow mesenchymal stromal cells support myeloma cell growth. Previous studies have suggested that direct and indirect interactions between malignant cells and bone marrow mesenchymal stromal cells result in constitutive abnormalities in the bone marrow mesenchymal stromal cells. DESIGN AND METHODS The aims of this study were to investigate the constitutiv...

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