El’gygytgyn Crater Lake, NE Siberia was investigated for sedimentological proxies for regional climate change with a focus on the past 65 ka. Sedimentological parameters assessed relative to magnetic susceptibility include stratigraphy, grain size, clay mineralogy and crystallinity. Earlier work suggests that intervals of high susceptibility in these sediments are coincident with warmer (interg...

Background: Systemic lupus erythematosus (SLE) could affect multiple parts of the eye. (1,2) Also, there is risk ocular toxicity associated with treatment, such as hydroxychloroquine.(3) Early diagnosis essential to avoid major complications. However, complaints eye discomfort may be vague, and various presentations pose challenges on rheumatologists. Knowing real-world prevalence problems in p...

Room-temperature quasi-ballistic electron transport in double-wall carbon nanotubes (DWNT) is demonstrated. Conductance dependence on the length was measured by submerging DWNTs into liquid mercury. The conductance plots show plateaus, indicating weak dependence of the electrode–tube–electrode electrical resistance on the length of the connecting nanotube. We infer a mean free path between 0.6 ...

Diode-pumped crystals provided recently new compact laser devices. We report the first end pumping of a La Ndl-xMgAEl,Ol,(LNA) crystal using a 200mW diode array (Spectra Diode Lab). We also rgport the first results obtained with a ImW diode (SONY). This C.W. laser can be tuned from 1.048~ to 1.086pm. Without selective elements in the cavity, the laser emits around 1.054pm with a threshold of 24...

Background Hydroxychloroquine (HCQ) is the cornerstone of systemic lupus erythematous (SLE or lupus) treatment, yet, optimal dosing HCQ in SLE unknown. Reducing dose to 5 mg/kg limit toxicity, as suggested by American Academy Ophthalmologists (AAO),(1) also predicts increased flares.(2) One study showed six-fold higher risk severe flares patients receiving AAO recommended dosing.(2) Therefore, ...

Here we present a new method for the sampling and quantitative extraction of dissolved He, Ne, Ar, Kr, and Xe from lake sediment samples leading to determinations of porewater noble gas concentration profiles and the isotopic ratios 3He/4He, 20Ne/22Ne, and 40Ar/36Ar. Bulk sediment is transferred from a sediment core into standard Cu sample tubes without exposure to the atmosphere or other gas r...

The development of multicellular organisms requires a balance between the cellular processes of proliferation, differentiation and death. These processes are important throughout the whole life of the organism. Daily, the DNA in our cells is under attack by agents that can cause damage. Thus, the cells have developed mechanisms to manage the DNA damage through activation of pathways leading to ...

Two years ago, we published an editorial demonstrating that submitted and papers in Journal of Applied Ecology were heavily skewed towards English-speaking authors from the Global North, with nearly 80% our more than 88% coming North America, Europe Oceania. This contribution provoked a strong response on social media, was followed by number studies further research outputs leading ecological c...

Retrieved from 49th Fall Meeting of the American Geophysical Union Abstracts (San Francisco, CA).Fricke, H. C., and Wing, S. L. (2004). Oxygen isotope and paleobotanicalestimates of temperature and δ18O–latitude gradients over North Americaduring the early Eocene. Am. J. Sci. 304, 612–635. doi: 10.2475/ajs.304.7.612Fyles, J. G. (1990). Beaufort formation (late tertiary) as s...

Many construction processes include installation of unique materials in specific locations in the facility being built: materials and locations must match before installation can take place. Mismatches due to delay and uncertainty in supplying materials or completing prerequisite work at those locations hamper field productivity. This is illustrated here using a model of a materials-management ...