نتایج جستجو برای: medullary thyroid cancer
تعداد نتایج: 982512 فیلتر نتایج به سال:
thyroid cancer, the most common endocrine malignancy worldwide, originates from follicular epithelial cells. it is classified as a well-differentiated thyroid carcinoma (wdtc), which includes both follicular (ftc) and papillary types (ptc), poorly differentiated thyroid carcinomas (pdtc), anaplastic thyroid carcinoma (atc), and/or arising from para-follicular calcitonin producing cells involve m...
BACKGROUND: Medullary thyroid cancer, a tumor of the parafollicular C cells, accounts for approximately 10% of all thyroid malignancies. An estimated 75% of cases are sporadic, and the remaining 25% are familial. METHODS: The author reviews the clinical features and diagnostic tests for this entity, as well as the surgical treatment of recurrent or persistent medullary carcinoma. RESULTS: Spora...
Thyroid cancer is one of the most common malignancies of endocrine glands, causing carcinomas, such as papillary, follicular, medullary, and anaplastic thyroid carcinomas. Due to the significance of thyroid carcinomas, identification of the main signaling pathways and the affecting mutations has been considered by researchers. Further studies on the dysregulation of oncogenes in signaling path...
A medullary thyroid carcinoma is a malignant tumor derived from the C-cells of the thyroid. Despite their distinct embryological origin, medullary thyroid carcinomas are exceptionally accompanied by a tumor derived from the follicular cells; this is defined as mixed medullary and follicular cell carcinoma. There have been controversies regarding the origin of this rare mixed thyroid carcinoma q...
Background: Familial Medullary Thyroid Cancer (FMTC) is hereditary in 25% of cases. Patients with an inherited form FMTC usually have a germline mutation the RET proto-oncogene (10q11.2); these mutations generally occur exons 10 (codons 618 and 620) 11 630, 631, 634).
 Methods: A narrative review articles focused on pathology familial medullary thyroid cancer was carried out using next dat...
BACKGROUND Papillary thyroid carcinoma is the most common thyroid cancer (85%). Follicular thyroid carcinoma is the second most common type of thyroid cancer, accounting for up to 10% of all thyroid cancers. Medullary thyroid carcinoma accounts for only 5-8% of thyroid cancers. Concurrent medullary, follicular, and papillary carcinomas of the thyroid gland are extremely rare and reported scarce...
Using immunohistochemistry, Fas/Apo-1 protein expression was investigated in thyroid cancers of 67 patients. Thyroid biopsies from twenty eight patients with benign thyroid diseases were also examined. The patients with thyroid cancer manifested a variable histology of the cancer, including 14 patients with follicular carcinoma, 48 with papillary carcinoma, 5 patients with medullary carcinoma. ...
the coexistence of medullary thyroid carcinoma (mtc), papillary thyroid carcinoma (ptc) and parathyroid adenoma is an uncommon clinical entity. here, we report a case of mtc, ptc, and parathyroid adenoma diagnosed incidentally on a routine physical examination of the neck for the work-up of diabetes. the patient had neither symptoms of hypercalcemia nor those related to mtc and ptc.
Thyroid cancer is one of the most common endocrine cancers in the body, which accounts for approximately 1.8% of all malignancies in Iran and its prevalence is reported to be higher among women than men .This type of cancer is classified into four main subgroups including papillary (PTC), follicular (FTC), medullary (MTC) and Anaplastic (ATC).To differentiate different types of cancer, biopsy m...
Medullary thyroid carcinoma is a neuroendocrine tumour originating from parafollicular C cells accounting for 5-10% of thyroid cancers. Increased understanding of disease-specific molecular targets of therapy has led to the regulatory approval of two drugs (vandetanib and cabozantinib) for the treatment of medullary thyroid carcinoma. These drugs increase progression-free survival; however, the...
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