The steady increase in life expectancy in our modern industrialized societies will not only lead to a significant change in demographics, but also in epidemiologic factors. This paper reviews current predictions for epidemiologic indicators and derives implications for the development of future health-enabling technologies. Methods: A literature search in PubMed/MEDLINE was conducted and severa...

This article contributes to the development of methods for analysing research funding systems by exploring the robustness and comparability of emerging approaches to generate funding landscapes useful for policy making. We use a novel dataset of manually extracted and coded data on the funding acknowledgements of 7,510 publications representing UK cancer research in the year 2011 and compare th...

Over the years several studies have demonstrated the ability to identify potential drug-drug interactions via data mining from the literature (MEDLINE), electronic health records, public databases (Drugbank), etc. While each one of these approaches is properly statistically validated, they do not take into consideration the overlap between them as one of their decision making variables. In this...

Whenever new sequences of DNA or proteins have been decoded it is almost compulsory to look at similar sequences and papers describing those sequences in order to both collect relevant information concerning the function and activity of the new sequences and/or know what is known already about similar sequences that might be useful in the explanation of the function or activity of the newly dis...

Current information extraction efforts in the biomedical domain tend to focus on finding entities and facts in structured databases or MEDLINE abstracts. We apply a gene and protein name tagger trained on Medline abstracts (ABGene) to a randomly selected set of full text journal articles in the biomedical domain. We show the effect of adaptations made in response to the greater heterogeneity o...

Using EndNote version 7.0, the authors tested the search capabilities of the EndNote search engine for retrieving citations from MEDLINE for importation into EndNote, a citation management software package. Ovid MEDLINE and PubMed were selected for the comparison. Several searches were performed on Ovid MEDLINE and PubMed using EndNote as the search engine, and the same searches were run on bot...

A database was created on the structure-functional organization of the locus-control regions (LCRs) in eukaryotic genomes. The database contains two sections including (i) formalized descriptions of LCRs and (ii) hypertextual description of the LCR structure and function. Both sections are linked by hypertexts between each other and with external databases such as TRRD, SWISS-PROT, EMBL, and Me...

OBJECTIVE To compare cardiac physical examination with echocardiography for evaluating systolic murmurs. QUALITY OF EVIDENCE Three databases were searched for studies comparing echocardiography and auscultation as to sensitivity and diagnostic accuracy: MEDLINE (Ovid Online), EMBASE, and Current

Objectives: To explore the phenomenon of adjectival modification in biomedical discourse across two genres: the biomedical literature and patient records. Methods: Adjectival modifiers are removed from phrases extracted from two corpora (three million noun phrases extracted from MEDLINE, on the one hand, and clinical notes from the Mayo Clinic, on the other). The original phrases, the adjective...