BACKGROUND Meconium and hair are two biological markers of in utero exposure to illicit drugs. OBJECTIVE To compare the sensitivity of the two tests for different drugs. SETTING Motherisk laboratory which tests in utero drug exposure in Toronto. METHODS Cocaine, benzoylecgonine, opiates, cannabis, benzodiazepines, methadone, and barbiturates were measured in pairs of hair and meconium sam...

background: previous studies have shown that meconium staining of the amniotic fluid may affect maternal and neonatal outcomes. in this study, we aimed to investigate the relationship between birth weight and meconium passage and its related factors in pregnant women.materials and methods: this matched case control study was conducted on a total of 200 newborns (100 as cases and 100 as controls...

Background: Since the treatment of meconium ileus is very different from other types of intestinal obstruction, it is very important to distinguish these two entities. The aim of this study was to assess sonographic findings to differentiate meconium ileus from other types of obstruction. Methods: This study was performed in Dr. Sheikh and Akbar hospitals, Mashhad Medical University of Science...

We agree that the passage of meconium in utero is not always due to intrauterine asphyxia and it may be a purely physiological event due to increasing maturity of the fetus. However, a bacterial endotoxin has been recently implicated in "causing the preterm labor and passage of meconium in utero(3). It is to be emphasized that only those neonates who have respiratory\distress with radiological ...

Objective-The purpose of this study was to find out prevalence ,risk factors, mode of delivery, & perinatal out come in Meconium stained amniotic fluid (MSAF) during delivery At term pregnancy.Study design-this retrospective study was conducted in MGMC&RI,puducherry with womens at 37-42 wks of gestation those were meconium stained amniotic fluid during labour & delivery.Different maternal outco...

BACKGROUND Meconium fatty acid ethyl esters (FAEE) constitute a biomarker of heavy fetal ethanol exposure. Our objective was to measure meconium FAEE in fetal sheep following daily, relatively moderate-dose ethanol exposure in late gestation, and to evaluate their utility in identifying fetal organ-system injury. METHODS Pregnant ewes received ethanol (0.75 g/kg; n = 14) or saline (n = 8) via...

The analysis of meconium for cocaine and metabolites has proved to be a reliable method for the detection of fetal cocaine exposure. Better sensitivity and a larger gestational window of detection have been demonstrated for meconium testing as compared with neonatal urine testing. Cocaine and cocaine metabolites, including benzoylecgonine, ecgonine methyl ester, cocaethylene, norcocaine, benzoy...

BACKGROUND Data on meconium bile acid composition in newborn babies of patients with intrahepatic cholestasis of pregnancy (ICP) are relatively scant, and changes that occur on ursodeoxycholic acid (UDCA) administration have not been evaluated. AIMS To investigate bile acid profiles in meconium of neonates from untreated and UDCA treated patients with ICP. Maternal serum bile acid composition...

1. The mucus glycoproteins in meconium from normal infants and from infants having cystic fibrosis with meconium ileus have been studied. 2. Whereas normal meconium contained about 50% protein-bound carbohydrate, the meconium from cystic fibrosis contained only about 10%. 3. Glycopolypeptides were prepared from the mucus of glycoproteins. The oligosaccharide units from this material were releas...

At present time, delivery room management of babies born through Meconium stained amniotic fluid (MSAF) often includes suctioning of the mouth and nose before the delivery of the shoulders. This addresses the concern that babies will inhale meconium present in the upper airway with their first breath putting them at risk of MAS. The rationale of routine perineal suctioning of all babies born th...