In this double-blind placebo-controlled randomized clinical trial, we investigated the influence of filgrastim administration on the quality of life (QOL) of refractory chronic sinusitis patients who did not respond to regular treatments. QOL was considered to be an important outcome measurement because apart from classic sinusitis parameters, it measures the overall burden of the symptomatolog...

Calcium fructoborate (CFB) at a dose of 110 mg twice per day was previously reported to improve knee discomfort during the first 14 days of treatment. In this study, 60 participants with self-reported knee discomfort were randomized into two groups receiving CFB or placebo. Initial levels of knee discomfort were evaluated by Western Ontario and McMaster Universities Arthritis Index (WOMAC) and ...

BACKGROUND Current interventions in amyotrophic lateral sclerosis (ALS) are focused on supporting quality of life (QoL) and easing pain with a multidisciplinary approach. OBJECTIVE Primary aim of this pilot work assessed feasibility, safety, tolerability and satisfaction of osteopathic manual treatment (OMT) in 14 ALS outpatients. METHODS Patients were randomized according to an initial sin...

OBJECTIVES The objectives of this study were to identify the available cross-cultural adaptations of the McGill Pain Questionnaire (MPQ), to describe the clinimetric testing that has occurred for each adaptation and to evaluate both the quality of the adaptation procedures and the clinimetric testing for each version. STUDY DESIGN AND SETTING This study is a systematic review. Searches of the...

Background & Aims: Fear of labor pain is a principal factor in pregnant women's tendency for cesarean section. This study was done to investigate the factors that affect quality and intensity of labor pain in order to decrease the rate of elective cesarean sections. Method: a prospective randomized study was performed on 208 parturient women in Maternity ward of afzalipour Hospital by using...

Deep brain stimulation (DBS) has shown promise for relieving nociceptive and neuropathic symptoms of refractory chronic pain. We assessed the efficacy of a new target for the affective component of pain, the anterior cingulate cortex (ACC). A 49-year-old man with neuropathic pain underwent bilateral ACC DBS. Patient-reported outcome measures were collected before and 2 years after surgery using...

BACKGROUND Chronic complex regional pain syndrome (CRPS) is a chronic pain condition that leads to sympathetic nervous system involvement and trophic changes. OBJECTIVE This study describes the use of acupuncture in a case study of CRPS. DESIGN, SETTING, AND PATIENT This is a single case report of a 34-year-old patient diagnosed with CRPS. INTERVENTION Acupuncture treatment including acup...

The purpose of this study was to the present a translated version of the McGill Pain Questionnaire to Brazilian Portuguese that adapted the original pain descriptors according to the Brazilian culture, aiming at its scientific validation. Initially, the original questionnaire was translated by 3 legally recognized translators fluent in English and in Brazilian Portuguese. The translations were ...