OBJECTIVES To investigate the Maslach Burnout Inventory-General Survey (MBI-GS) and the Utrecht Work Engagement Scale (UWES) for their ability to identify non-sicklisted employees at increased risk of long-term sickness absence (LTSA). METHODS One-year prospective cohort study including 4,921 employees participating in occupational health surveys in the period 2008-2010. The MBI-GS and UWES w...

This paper concentrates on two key areas connected with business informatics, i.e., business informatics management and the role of ICT in promoting sustainable development. The surveys mentioned in this paper show that organisations in the Czech Republic do not devote sufficient attention to these areas and thus lag behind organisations in other developed countries. To help enterprises with th...

The dimensional structure of the Maslach Burnout Inventory-Student Survey (MBI-SS) was investigated using data collected from three samples of Chinese students in two high schools, a university, and a nursing school, respectively (total N = 1,499; 36% males, 64% females; M age 19.0 yr., SD = 1.3). Single group Confirmatory Factor Analyses corroborated the hypothesized three-factor model for the...

During a 17-year period (1966-1983), 519 patients received renal allografts at the Johannesburg Hospital. Ten patients developed mycobacterial infections (MBI) in their post-transplant perio4 — a prevalence of 1,7%. Eight were dueto Mycobacteriumtuberculosis (M. tuberculosis); of the remaining two, one was due to Mycobacterium kansasii and one to MycobacteriunT forthuitum. Two patients died as ...

Inhibition of cytochrome P450 (CYP) 3A4 is the major cause of drug-drug interactions (DDI). We have previously reported that the genetic variation of CYP3A4 significantly affected the inhibitory profiles of typical competitive inhibitors. In addition to competitive inhibition, some clinically significant DDI are attributable to mechanism-based inhibition (MBI). However, the differences in the M...

A series of fluoroquinolone compounds (compounds 1-9), which contain a common quinolone scaffold, inactivated the metabolic activity of CYP3A. The purpose of this study was to identify mechanism-based inhibition (MBI) among these fluoroquinolone compounds by metabolite profiling to elucidate the association of the substructure and MBI potential. Reversibility of MBI after incubation with potass...

BACKGROUND Geriatric depression is associated with the overall quality of life (QOL). However, how depressive symptoms affect the different domains and facets of QOL in older adults, and whether depressive symptoms mediate the relationship between physical disability and QOL in older adults are unclear. METHODS A total of 490 ambulatory community-dwelling older adults aged 65 years or above w...

OBJECTIVE To investigate the relationship between grip and pinch strength and independence in activities of daily living (ADL) in stroke patients. METHODS Medical records of 577 stroke patients from January 2010 to February 2013 were retrospectively reviewed. Patients' grip and pinch strength of both hemiplegic and non-hemiplegic hands and the Korean version of Modified Barthel Index (K-MBI) ...