CONTEXT Vaccine development to prevent congenital cytomegalovirus (CMV) infection has been impeded by the uncertainty over whether maternal immunity protects the fetus. OBJECTIVE To determine whether the presence of maternal antibodies to CMV significantly reduces the risk of congenital CMV infection in future pregnancies. DESIGN, SETTING, AND PARTICIPANTS Cohort study of 3461 multiparous w...

Background: Congenital toxoplasmosis results from vertical transmission of the Toxoplasma gondii parasite mother to fetus after a primary maternal infection. The risk fetal contamination is higher later term Conversely, severe infection decreases with term; third trimester infections are most often asymptomatic at birth.

background and objective: hypertensive disorders complicating pregnancy are common and from one of the deadly triad, along with hemorrhage and infection that contribute greatly to prenatal and maternal morbidity and mortality in the developing countries. this study was designed to investigate the relationship between maternal hypothyroidism and pre-eclampsia. materials and methods: in a prospec...

Background: The aim of our study is to compare the maternal mortality between those who are infected with COVID-19 infection and not. Our was done at Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, which included 2 groups: group 1- pregnant women infection, 2- without infection. Methods: prospective comparative study, over 250 antenatal patients admitted centre, status confirmed eith...

While antibody responses to neurovirulent pathogens are critical for clearance, the extent to which antibodies access the nervous system to ameliorate infection is poorly understood. In this study on herpes simplex virus 1 (HSV-1), we demonstrate that HSV-specific antibodies are present during HSV-1 latency in the nervous systems of both mice and humans. We show that antibody-secreting cells en...

normal 0 false false false en-us x-none ar-sa objective: to compare the effect of betamethasonemethasone (betamethasone) and dexamethasonemethasone (dexamethasone) on maternal white blood cell (wbc) and differential count, erythrocyte sedimentation rate (esr), apgar score, maternal and fetal plasma glucose and length of admission to delivery , gestational age at delivery in women at risk of pre...

We reviewed studies that reported results of systematic cytomegalovirus (CMV) screening on fetuses and/or live-born infants. The overall birth prevalence of congenital CMV infection was 0.64%, but varied considerably among different study populations. About 11% of live-born infants with congenital CMV infection were symptomatic, but the inter-study differences in definitions of symptomatic case...

Varicella zoster virus (VZV) infection can be serious for pregnant women and their babies, although it is rare. The implications of primary VZV infection vary with the gestational age at infection. For the mother, the risk of severe illness is greatest after mid-pregnancy, when she is relatively immunocompromised. For the fetus, the risk of congenital infection is greatest when maternal infecti...

We describe two unusual cases of congenital toxoplasmosis, one occurring after preconception maternal infection with cervical adenopathies and the other occurring after maternal infection at the very end of pregnancy with maternal seronegativity at delivery. These documented cases of congenital toxoplasmosis demonstrate the value of extending the serologic monitoring period during pregnancy, ac...

BACKGROUND Scarce data exist about screening, diagnosis and prognosis of non-primary Cytomegalovirus (CMV) during pregnancy. We aimed to examine antenatal diagnosis of maternal non-primary CMV infection and to identify risk factors for congenial CMV disease. METHODS Retrospective cohort of 107 neonates with congenital symptomatic CMV infection, following either primary (n = 95) or non-primary...