this study investigated the presence of mast cells in inflammatory aural polyps using light microscopy. the number of mast cells was increased in all examined cases and varied from 2.33 to 41.54 per mm2• the cells were located most commonly around small blood vessels. occurrence of mast cells was not different in various types of polyps, but their density was severely increased in active inflam...

background & objectives: odontogenic cysts are among the most frequent destructive lesions of jaws which their pathogenesis and growth mechanism are not cleared. with respect to different roles of mast cells, they may play a role in the pathogenesis and growth of odontogenic cysts. the aim of present study was to evaluate mast cells in the most common odontogenic cyst. methods: thirty  para...

Mast Cell Leukemia (MCL), a rare subtype of systemic mastocytosis is defined by bone marrow involvement as atypical and aleukemic mast cells, if more than 20% and less than 10% of peripheral WBCs are mast cells, respectively. We met a case of aleukemic MCL presenting with anemia and ascites for 2 years, referred for BM evaluation, suspicious of leukemia. Our findings included BM involveme...

Background: Spermatogenesis is under the control of variety of factors, which include mast cells. Any changes in testicular mast cells’ number and distribution resulting in deterioration of comlex regulation and fine-turning of spermatogenesis. Increased number of mast cells and their abnormal spread pattern have been described in the testis with fertility disturbances. Mast cells’ tryptase enz...

We examined the impact of chronic stress on rat growth rate and intestinal epithelial physiology and the role of mast cells in these responses. Mast cell-deficient (Ws/Ws) rats and +/+ littermate controls were submitted to water avoidance stress or sham stress, 1 h/day, for 5 days. Seven hours after the last sham or stress session, jejunal segments were mounted in Ussing chambers, in which secr...

The purpose of present study was determination of number changes of mast cells in a honey treated experimental model of third degree burn. A third degree burn was made in 24 adult female rats by direct contact of skin with boiling water for 8 seconds. Rats were divided randomly into four groups. Group 1: Burns of this group remained untreated (control group). Groups 2 and 3: Burns of these grou...

The purpose of present study was determination of number changes of mast cells in a honey treated experimental model of third degree burn. A third degree burn was made in 24 adult female rats by direct contact of skin with boiling water for 8 seconds. Rats were divided randomly into four groups. Group 1: Burns of this group remained untreated (control group). Groups 2 and 3: Burns of these grou...

Mast cells are a heterogeneous population of granulocytic cells in the immune system. Mast cell granules contain numerous mediators, including neurotransmitters, cytokines, chemokines and lipid-derived factors. In addition to their well-known role in immune inflammation, the presence of mast cells in the meninges and perivascular space in the central nervous system points to their role in brain...

background: squamous cell carcinoma (scc) is the most common malignancy in oral cavity. angiogenesis is essential for the development and progression of scc. recently, some studies have reported that mast cells may play a role in tumor progression via promoting angiognesis. since the results of various studies on the role of mast cells in tumor progression is not uniform, the aim of this study ...