BACKGROUND AND AIMS Fluid resuscitation of severely injured patients has shifted over the last decade toward less crystalloids and more blood products. Helsinki University trauma center implemented the massive transfusion protocol in the end of 2009. The aim of the study was to review the changes in fluid resuscitation and its influence on outcome of severely injured patients with hemodynamic c...

Methods Total of 406 patients (f/m N=103/303) were studied in the ICU in 2011; 21 (5.17%) males were observed,. HGB in OR prior to surgery was: 127.43 g/L(SD±19.4; range 85-165; median 129g/L). Patients were divided into two groups, according to the quantity of RBCs received. Group 1 (N=15) received 5-9 units RBCs; group 2 (N=6) received ≥10 units RBCs. EuroSCORE II was used for operation risk ...

Massive bleeding in trauma patients is a serious challenge for all clinicians, and an interdisciplinary diagnostic and therapeutic approach is warranted within a limited time frame. Massive transfusion usually is defined as the transfusion of more than 10 units of packed red blood cells (RBCs) within 24 h or a corresponding blood loss of more than 1- to 1.5-fold of the body's entire blood volum...

background: increased costs and mortality associated with inappropriate blood transfusions have led to investigations about blood request and blood transfusion techniques. we investigated the transfusion status in patients who underwent orthopedic surgery in poursina hospital (rasht, iran) to optimizing blood usage and determine if a scheduled transfusion program for every orthopedic surgery co...

We describe a rare case of Mallory-Weiss tear with massive hematemesis at 38 weeks' gestation. A 35-year-old woman presented with epigastralgia followed by massive hematemesis. An emergency endoscopy indicated active pulsatile bleeding at the esophagocardial junction. Although an emergency endoscopic hemostasis was successful, late decelerations without acceleration on cardiotocogram were obser...

Blood transfusion is frequent in critical care. Transfusion raises the mass of transfused blood components and is lifesaving in acute hemorrhage. In massive transfusion (>10 units of red blood cells), early attempts to restore coagulation function appear helpful. Transfusion in non-bleeding patients is largely prophylactic, is seldom evidence-based, and may be deleterious. In hemodynamically st...

BACKGROUND Coagulopathy is a consequence of severe trauma, especially in massively transfused patients (>or=10 units of red blood cells in 24 hours), and is associated with increased mortality. We hypothesized that recombinant factor VIIa (rFVIIa) administered to massive transfusion patients before transfusion of 8 units of blood (early) would reduce transfusion requirements compared with rFVII...

In 1818, Blundell, an English obstetrician, performed blood transfusion to 11 parturients in order to resolve the massive hemorrhage, in which 5 were successfully treated, which largely improved the development of blood transfusion. In 1901, Landsteiner found the first human blood-group system (ABO blood groups), after which the discovery of the importance of cross-matching of blood between don...

BACKGROUND Transfusion-related acute lung injury (TRALI) is a rare, but potentially fatal, complication of blood product transfusion, manifesting as acute respiratory distress syndrome. In most cases, TRALI is associated with massive transfusion of fresh frozen plasma and platelets. CASE REPORT A 38-year-old-woman at 40 weeks gestation was admitted to hospital with spontaneous labor contracti...