background :delay in diagnosis and treatment of acute appendicitis (aa) results in an increased rate of perforation, postoperative morbidity, mortality and hospital length of stay. several biochemical parameters including white blood cell (wbc) count, c-reactive protein (crp), interleukin-6 (il6) and procalcitonin (pct) have been used to further improve the clinical diagnosis of aa. the aim of ...

background gaucher’s disease (g.d.) is an autosomal recessive disorder resulting from the accumulation of glucocerebrosidase in the cells of macrophage-monocyte system as a result of a deficiency in lysosomal glucocerebrosidase. this enzyme is encoded by a gene on chromosome-1. here we report a case of gaucher’s disease .g.d is rare in yazd. case reports we reported a patient that presented wit...

abstract background thalassemia is common in the iranian population, and it must be considered in the differential diagnosis of the microcytic hypochromic anemia. the molecular analysis of β-thalassemia is necessary for prenatal molecular diagnosis. α-thalassemia caused by loss of function of either one of the two duplicated α-globin genes or in less frequent non deletion mutations mostly locat...

conclusions igm alone is not a marker for viral shedding in genital tract. molecular testing in conjunction of igg test should be evaluated as an option to determine hsv status, and applied for research on hsv genital infections records. methods two hundred and eight females were included in the study; igm antibodies against hsv1/2 were detected in serum samples; the real-time polymerase chain ...

orofacial granulomatosis(ofg) is a granulomatous disease of the orofacial region which appears usually as a persistent and/or recurrent labial soft tissues swelling in the orofacial region and is characterized histologically by a granulomatous inflammation. ofg may cause significant cosmetic and functional problems but can be prevented if the disease is diagnosed early and promptly treated. the...

results a total of 600 women were screened for t. vaginalis infection and this infection was diagnosed in 9 (1.5%) and 13 cases (2.1%) using the wet mount and culture methods, respectively. the age and husband occupation were significantly associated with an increased risk of trichomoniasis in the infected cases (p < 0.05 and p < 0.001, respectively); other variables, including the patients' oc...

background &amp; objectives:  accurate differentiation of eczema and psoriasis can be difficult, especially in areas of palm and sole. this study was designed to evaluate histopathological features and identify statistically significant parameters in distinguishing palmoplantar psoriasis from eczema of these regions in patients referring to razi skin hospital, tehran, iran. methods: in a cross-...

background: tuberculous meningitis (tbm) is a severe form of extra pulmonary tuberculosis with high mortality and morbidity rate in all age group patients specific in adults and children. the incidence and prevalence are not exactly known in iran. in this study, we tried to evaluate the role of rapid diagnosis and to find out the highest risk group patients.  methods:totally, 1783-suspected pa...