The classical mathematical theory of population genetics considered, for simplicity, almost exclusively one-locus systems. In the last two decades much work has been done on two-locus and, less frequently, multi-locus systems. This research has usually involved investigating properties of systems with given, and usually rather special, fitness parameters. Real genetic fitness systems are undoub...

Equilibrium behavior of two-locus mutation-selection balance models is analyzed using perturbation techniques. The classical result of Haldane for one locus is shown to carry over to two loci, if fitnesses are replaced by marginal fitnesses. If the fitness of the double heterozygote is smaller than would be produced by a multiplicative model, as in additive or quantitative fitness models, the d...

OBJECTIVE To evaluate the influence of core thickness and fabrication stages on the marginal accuracy of IPS e.max Press crowns. MATERIALS AND METHODS Twenty IPS e.max Press crowns, 1.5mm thick, were fabricated on metal dies. The crowns had two different core thicknesses, 0.8mm for group A and 1mm for group B, ten for each group. Marginal gap was measured after each stage of core fabrication,...

Public fitness service facilities are one of the most important factors affecting national fitness. Analyzing distribution characteristics and influencing public is great significance to optimizing services. In this paper, using population concentration index consistency test, recent proximity index, coupling coordinated development model, buffer analysis, correlation combined with ArcGis 10.7 ...

The Breeder Genetic Algorithm (BGA) was designed according to the theories and methods used in the science of livestock breeding. The prediction of a breeding experiment is based on the response to selection (RS) equation. This equation relates the change in a population's fitness to the standard deviation of its fitness, as well as to the parameters selection intensity and realized heritabilit...

The effect of lysis timing on bacteriophage (phage) fitness has received little theoretical or experimental attention. Previously, the impact of lysis timing on phage fitness was studied using a theoretical model based on the marginal value theorem from the optimal foraging theory. An implicit conclusion of the model is that, for any combination of host quantity and quality, an optimal time to ...

• Species that exhibit adaptive plasticity alter their phenotypes in response to environmental conditions, thereby maximizing fitness in heterogeneous landscapes. However, under demographic source-sink dynamics, selection should favor traits that enhance fitness in the source habitat at the expense of fitness in the marginal habitat. Consistent with source-sink dynamics, the perennial blueberry...

I N the last decade the theoretical consequences of the joint effects of recombination rate and fitness interactions between loci have been studied by KIMURA (1956, 1965) , KOJIMA (1959‘ a,b), LEWONTIN and KOJIMA (1960), LEWONTIN (1964 a,b.c), and FELSENSTEIN (1965). Several observations support the relevance of this body of theory to natural and laboratory populations. Non-random associaticins...