Microbial infections of various types of wounds are a challenge to the treatment of wounds and wound healing. The study was to investigate antimicrobial and antioxidant properties of methanol leaf and stem bark extracts of Kigelia africana and methanol leaf and root extracts of Strophanthus hispidus and also to determine wound healing properties of the extracts. The antimicrobial activities of ...

Oxidative stress has an important role in the pathogenesis of doxorubicin (DOX)-induced nephrotoxicity. The aim of this study was to investigate the nephroprotective effects of fullerenol (FLR), an antioxidant agent, on DOX-induced nephrotoxicity. The investigation was carried out on adult female Sprague Dawley outbred rats with chemically induced breast cancer (1-methyl-1-nitrosourea; 50 mg/kg...

Renal disorders have always remained a major area of concern for physicians since a long time. It is the 9th leading cause of death in United States. Incidence of kidney diseases leading to kidney failure is increasing day by day. A large number of chemicals in common use are potential renal toxins. The use of herbal drugs for the prevention and treatment of various diseases is constantly devel...

Article history: Received on: 26/10/2016 Accepted on: 30/12/2016 Available online: 30/05/2017 The protective effect of wheat germ oil (WGO) as a natural antioxidant was evaluated against carbon tetrachloride (CCl4)-induced nephrotoxicity, genotoxicity and alterations in gene expression in mice kidney. WGO group: received olive oil orally for 2 days then WGO orally for 8 days, CCl4 group: receiv...

Trifolium alexandrinum is traditionally used in various human ailments, including renal dysfunctions. The present experiment was designed to investigate antioxidant and nephroprotective effect of T. alexandrinum methanolic extract (TAME) against CCl4-induced oxidative stress in albino rats. Results of in vitro study revealed significant (P < 0.05) antioxidant effects. The ameliorative role of T...

Background: Sea cucumbers have number of one a pharmacological effects counting anticancer, anticoagulant, anti-inflammatory, antioxidant, and wound healing. Biological properties therapeutic benefits can be connected to the presence wide cluster bioactive compounds particularly triterpene glycosides (saponins). Aims: The present study aimed explore hepatoprotective nephroprotective activity cu...

Curcumin is the essential ingredient of turmeric and one most potent antioxidants. It also has several biological capabilities, including anti-inflammatory, anticarcinogenic, anticoagulant, antidiabetic, antiviral, antibacterial, antifungal effects. Therefore, curcumin a significant potential for treatment control various diseases. In kidney disorders like chronic disease (CKD) diabetic nephrop...

The antioxidant activities of the methanol extracts from the leaves and stems of Celtis africana (Ulmaceae) were assessed in an effort to validate the medicinal potential of the subterranean part of the herb. The antioxidant activity and phenolic contents of the stem as determined by the DPPH, proanthocyanidins, total phenols, the flavonoids, and total flavonols were higher than that of the lea...