Meningioma accounts for approximately one-third of primary central nervous system tumors. Most meningiomas are benign, although up to one third are classified as atypical or malignant. We describe a 63-year Caucasian male presenting with pleural metastases from an intracranial meningioma. Distant metastases from meningiomas are infrequently found in clinical practice and mostly are associated w...

This investigation was conducted to determine the ability of 201Tl brain SPECT with respect to preoperative prediction of lesional aggressiveness of meningioma. Fifty-nine lesions in 42 patients were examined. Early (15 min) and late (3 h) SPECT were obtained. Early uptake ratio (ER; lesion to normal brain average count ratio), late uptake ratio (LR) and the ratio of LR to ER (L/E ratio) were c...

Dr. Baltazar Leão Reis – Avenida Francisco Sales 1813 / 102 30150-221 Belo Horizonte MG Brasil. E-mail: [email protected] Meningiomas are tumors originating from meningothelial cells of the arachnoid membrane and are benign in most cases, corresponding to about 15% to 18% of all primary tumors of the central nervous system (CNS). Extracranial metastases of meningiomas are rare and occur...

The role of PDGF-B and its receptor in meningeal tumorigenesis is not clear. We investigated the role of PDGF-B in mouse meningioma development by generating autocrine stimulation of the arachnoid through the platelet-derived growth factor receptor (PDGFR) using the RCAStv-a system. To specifically target arachnoid cells, the cells of origin of meningioma, we generated the PGDStv-a mouse (Prost...

The GTPase-activating protein RLIP76 is overexpressed in and correlates with the pathological grade of many malignant tumor cells. But the potential correlation between RLIP76 and clinical outcomes in patients with meningioma remains unknown. In this study, we examined the expression of RLIP76 in meningioma and correlated the RLIP76 expression to the patient outcome. RLIP76 expression in tumor ...

INTRODUCTION We report a case of Rhabdoid meningioma in an eight-year-old child which is the fifth case in the world according to our knowledge. MATERIAL AND METHOD An 8-year-old girl was seen in our University Clinic of Neurosurgery with one month history of increasing headaches, vomiting and increasing frequency of grand mal seizures (known history of epilepsy). Her past medical history was...

Intracranial meningioma with intratumor metastasis have been occasionally reported. However, to our knowledge, there are almost no reports of malignant tumors initially discovered due to metastasis to meningioma. A 74-year-old woman presented with amnesia. Magnetic resonance imaging showed a well-defined mass arising from falcotentorial junction and homogeneous enhancement. Histopathologic find...

OBJECTIVE To investigate the potential involvements of E-cadherin and beta-catenin in meningioma. METHODS Immunohistochemistry staining was performed on samples from patients with meningioma. The results were graded according to the positive ratio and intensity of tissue immunoreactivity. The expression of E-cadherin and beta-catenin in meningioma was analyzed by its relationship with WHO2007...