Acanthosis nigricans (AN) is a skin disorder characterized by focal or diffuse hyperkeratosis symmetric hyperpigmentation of the skin and oral cavity mucosa. Various neoplasms, especially gastrointestinal adenocarcinomas are associated with acanthosis nigricans (AN malignant). Chemotherapy may cause regression of skin lesions. The etiology of AN is not clear. A role of growth factors such as me...

Confluent and reticulated papillomatosis is a rarely reported dermatosis of unknown origin. It is similar to nummular and confluent papillomatosis; punctate, pigmented verrucose papillomatosis; acanthosis nigricans; pseudoacanthosis nigricans; benign acanthosis nigricans; pseudoatrophoderma colli; tinea versicolor; Darier's disease; epidermodysplasia verruciformis; and verruca plana. Treatment ...

Methods We performed a cross sectional analytic observational study. One hundred twenty three obese children, ages 10 – 14 years with and without acanthosis nigricans got examined for insulin resistance using Homeostasis Model Assessment of Insulin Resistance Index (HOMA-IR). Diagnosis of acanthosis nigricans is confirmed by a dermatologist. This study took place in Wenang district, Manado, Nor...