background & aim: malignant fibrous histiocytoma (mfh), is the most common soft tissue sarcoma in adults and is frequently seen is elderly. this lesion is so rare in bones and if seen, is common in long bones and the incidence of the lesion in maxillofacial bones is uncommon. in addition, maxilla is an unusual site for malignant fibrous histiocytoma (mfh). the aim of this article was to report ...

epidemiology studies have demonstrated inconsistent associations between type 2 diabetes mellitus and the risk of malignant melanoma. to this end, the aim was to perform a meta-analysis of cohort studies.medline, pubmed, embase and the cochrane library were searched up to february 2014. cohort studies addressing the relative risk of type 2 diabetes mellitus on malignant melanoma were included i...

purpose: true neoplasm (adenocarcinoma) of retinal pigment epithelium (rpe) is very rare since it can be misdiagnosed as intraocular malignant melanoma it is of importance to know the clinical and pathologic aspects of this neoplasm. here, we report a case of adenocarcinoma of rpe. methods: case report. results: a 60-year-old man with progressive loss of the vision of the right eye was enucleat...

introduction: the gastrin releasing peptide (grp) receptor is over expressed in a variety of common human tumors. radiolabeled bombesin analogues have exhibited high binding affinity for these receptors. the aim of this study was to assess the value of a new 99mtc-bombesin analog in the differentiation of malignant from benign breast tumors. methods: 99mtc-bombesin scans were performed in 21 pa...

salivary  gland  tumors  accounts  for  less  than  1%  of  all  tumors.  minor  salivary  gland  tumors (msgts) are uncommon and make up about 10% of all salivary gland neoplasms. the clinical and histopathological distribution of these tumors vary geographically. a case of a 38 yr old man with a minor salivary gland mass at chin region isreported here. the tumor invaded into the anterior surf...

malignant peripheral nerve sheath tumor (mpnst) is a rare malignant tumor that develops either from a preexisting neurofibroma or de novo. the cell of origin is believed to be the schwann cell and possibly other nerve sheath cells. in this report, we describe a rare case of mpnst that arise from the socket of second left maxillary molar that has been already extracted in a young man. he was ref...

protein losing enteropathy (ple) as an initial finding of lymphoma, is extremely rare in childhood. we describe clinical and pathological features of an unusual case of gastrointestinal lymphoma presented with ple as a sole manifestation. differential diagnosis in children presenting with ple is critical because early diagnosis and treatment are important for survival in patients with lymphoma.

vitiligo is a disease that results in depigmented areas in the skin. it may develop at any age but the average age at onset is 20 years. association of vitiligo and melanoma has been commonly reported, but malignancies other than melanoma have been rarely associated with vitiligo. we report a 73‑year‑old patient with new onset vitiligo who developed esophageal adenocarcinoma in the following ye...

introduction: the incidence of malignant melanoma is increasing at a rate greater than any other human cancer. although melanoma accounts for only 4 percent of all dermatologic cancers, it is responsible for 80 percent of deaths from skin cancer; only 14 percent of patients with metastatic melanoma survive for five years. the optimal therapy varies with the stage of the disease. surgical excisi...

abstract primary cardiac tumors are rare in all ages. their reported prevalence ranges from 0.001 to 0.03 percent in autopsy series. 25 percent of primary cardiac tumors are considered to be malignant, the majority of which are sarcomas. on account of the late presentation of symptoms in malignant heart masses, finding locally infiltrative tumors or systemically widespread cases at initial pres...